1569895-72-2

Basic information

• Product Name: C₃₁H₃₈Cl₂FN₅O₅
• Synonyms: C₃₁H₃₈Cl₂FN₅O₅
• CAS NO: 1569895-72-2
• Molecular Weight: 650.578
• Mol File: 1569895-72-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₃₈Cl₂FN₅O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₃₈Cl₂FN₅O₅(1569895-72-2)
• EPA Substance Registry System: C₃₁H₃₈Cl₂FN₅O₅(1569895-72-2)

Safety Data

• Hazardous Substances Data: 1569895-72-2(Hazardous Substances Data)

Upstream product

• 877399-50-3 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 877399-52-5 crizotinib 

Relevant articles and documents

A novel approach for the synthesis of Crizotinib through the key chiral alcohol intermediate by asymmetric hydrogenation using highly active Ir-Spiro-PAP catalyst

A novel approach for the synthesis of Crizotinib (1) is described. In addition, new efficient procedures have been developed for the preparation of (S)-1-(2,6-dichloro-3-fluorophenyl)ethanol (2) and tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl) piperidine-1-carboxylate (4), the key intermediates required for the synthesis of Crizotinib.