1571113-48-8

Basic information

• Product Name: S-(4-fluorobenzoyl)thiohydroxylamine
• Synonyms: S-(4-fluorobenzoyl)thiohydroxylamine
• CAS NO: 1571113-48-8
• Molecular Weight: 171.195
• Mol File: 1571113-48-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-(4-fluorobenzoyl)thiohydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: S-(4-fluorobenzoyl)thiohydroxylamine(1571113-48-8)
• EPA Substance Registry System: S-(4-fluorobenzoyl)thiohydroxylamine(1571113-48-8)

Safety Data

• Hazardous Substances Data: 1571113-48-8(Hazardous Substances Data)

Upstream product

• 403-44-1 4-fluorobenzenecarbothioic S-acid 

Downstream Products

• 1259992-51-2 C₆H₄FCOSNHCOC₆H₅ 
• 1571113-49-9 C₁₄H₁₀FNOS 

Relevant articles and documents

Design, Synthesis, and Cardioprotective Effects of N-Mercapto-Based Hydrogen Sulfide Donors

Hydrogen sulfide (H2S) is a signaling molecule which plays regulatory roles in many physiological and/or pathological processes. Therefore, regulation of H2S levels could have great potential therapeutic value. In this work, we report the design, synthesis, and evaluation of a class of N-mercapto (N-SH)-based H2S donors. Thirty-three donors were synthesized and tested. Our results indicated that controllable H2S release from these donors could be achieved upon structural modifications. Selected donors (NSHD-1, NSHD-2, and NSHD-6) were tested in cellular models of oxidative damage and showed significant cytoprotective effects. Moreover, NSHD-1 and NSHD-2 were also found to exhibit potent protective effects in a murine model of myocardial ischemia reperfusion (MI/R) injury.