157729-39-0

Basic information

• Product Name: 4-(2-bromoethynyl)-benzonitrile
• Synonyms: 4-(2-bromoethynyl)-benzonitrile
• CAS NO: 157729-39-0
• Molecular Weight: 206.041
• Mol File: 157729-39-0.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 4-(2-bromoethynyl)-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-bromoethynyl)-benzonitrile(157729-39-0)
• EPA Substance Registry System: 4-(2-bromoethynyl)-benzonitrile(157729-39-0)

Safety Data

• Hazardous Substances Data: 157729-39-0(Hazardous Substances Data)

Upstream product

• 3032-92-6 4-cyanophenylacetylene 
• 623-00-7 4-bromobenzenecarbonitrile 
• 75867-40-2 4-[2-(trimethylsilyl)ethynyl]benzonitrile 
• 105-07-7 4-cyanobenzaldehyde 
• 131356-52-0 2,2-dibromo-1-(4-cyanophenyl)ethene 

Downstream Products

• 1206482-99-6 4-(5-phenyl-oxazol-2-ylethynyl)-benzonitrile 
• 1228672-43-2 4-(2-((S)-4-isopropyl-2-oxooxazolidin-3-yl)ethynyl)benzonitrile 
• 1285537-25-8 4-((trans-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)ethynyl)benzonitrile 
• 1285537-18-9 4-((trans-4-(tert-butyl)cyclohexyl)ethynyl)benzonitrile 
• 1379658-15-7 4-(benzo[d]oxazole-2-carbonyl)benzonitrile 
• 62856-06-8 4-[2-(4-methylphenyl)ethynyl]benzonitrile 
• 1422721-71-8 (E)-N-benzyl-N-(2-(4-cyanophenyl)-1-iodovinyl)-4-methylbenzenesulfonamide 
• 1422721-72-9 (E)-N-benzyl-N-(1-bromo-2-(4-cyanophenyl)vinyl)-4-methylbenzenesulfonamide 
• 1467024-11-8 (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-{[(4-cyanophenyl)ethynyl]thio}tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 1467024-13-0 (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-{[(2R,3R,5R,6S)-4,5-diacetoxy-2-(acetoxymethyl)-6-{[(4-cyanophenyl)ethynyl]thio}tetrahydro-2H-pyran-3-yl]oxy}tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 20099-89-2 4-Cyanophenacyl bromide 
• 1638667-41-0 (Z)-4-(2-bromo-1-chloro-3-(5-oxotetrahydrofuran-2-yl)prop-1-en-1-yl)benzonitrile 

Relevant articles and documents

Chloramine Salt Mediated Oxidative Halogenation of Terminal Alkynes with KI or NaBr: Practical Synthesis of 1-Bromoalkynes and 1-Iodoalkynes

A direct oxidative halogenation of terminal alkynes has been realized using chloramine-B as the oxidant and KI or NaBr as the halogen source. This reaction enables a general and practical access to synthetically valuable 1-bromoalkynes and 1-iodoalkynes i

Palladium-Catalyzed Carbonylation in the Synthesis of N-Ynonylsulfoximines

Palladium-catalyzed carbonylation reactions with Cr(CO)6 as carbonyl source are key for the preparation of N-ynonylsulfoximines from NH-sulfoximines and bromoalkynes. The couplings proceed at room temperature with a wide range of substrate combinations affording the corresponding products in good yields. (Figure presented.).

Nickel-Catalyzed Reductive 1,2-Dialkynylation of Alkenes Bearing an 8-Aminoquinoline Directing Group

An unprecedented nickel-catalyzed reductive 1,2-dialkynylation of alkenes bearing an 8-aminoquinoline directing group has been developed. This method proceeded through a migratory insertion/reductive-coupling process under mild conditions with a wide substrate scope and good functional group tolerance, providing direct access to the synthetically flexible 1,5-diynes. Moreover, the 1,2-dialkynylation products could be further converted to borate-ester- or azide-functionalized 1,5-dienes, ditriazole, β-diyne primary amide, and trisubstituted benzene.