15814-19-4

Basic information

• Product Name: Benzenemethanamine, N-cyclopentylidene-
• CAS NO: 15814-19-4
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• Mol File: 15814-19-4.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-cyclopentylidene-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-cyclopentylidene-(15814-19-4)
• EPA Substance Registry System: Benzenemethanamine, N-cyclopentylidene-(15814-19-4)

Safety Data

• Hazardous Substances Data: 15814-19-4(Hazardous Substances Data)

Upstream product

• 7148-07-4 1-pyrrolidinocyclopent-1-ene 
• 100-46-9 benzylamine 
• 120-92-3 cyclopentanone 

Downstream Products

• 136936-07-7 1-allyl-1-N-benzylaminocyclopentane 
• 143425-83-6 1,2,4,5-tetrahydro-3H-5-methylspiro 
• 97475-96-2 ethyl 1-Benzyl-1,4,5,6-Tetrahydrocyclopenta[b]Pyrrole-2-Carboxylate 
• 1150617-92-7 2-chloro-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one 
• 911405-87-3 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 1-oxide 
• 117890-55-8 2-chloro-6,7-dihydro-5H-cyclopenta[b]pyridine 
• 15205-23-9 N-cyclopentylbenzylamine 
• 1429044-22-3 1-benzyl-1'-(2,2,2-trifluoroacetyl)-4,5-dihydro-1H,1'H-spiro[cyclopenta[b]pyrrole-3,4'-pyridin]-2(3aH)-one 

Relevant articles and documents

Short Total Synthesis of (±)-γ-Lycorane by a Sequential Intramolecular Acylal Cyclisation (IAC) and Intramolecular Heck Addition Reaction

An intramolecular acylal cyclisation (IAC) approach to the synthesis of a range of bicyclic heterocycles is reported. As an example of the utility of the IAC reaction, the methodology was applied in a protecting-group-free five-step total synthesis of (±)-γ-lycorane, incorporating a new intramolecular Heck addition reaction to generate the pentacyclic core structure of the natural product in good yield.

METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS

The invention relates to a method of producing a WEE1 inhibitor of formula (1A) useful in the treatment of pathological conditions characterized by excessive cell proliferation, such as cancer. In some embodiments, the invention relates to methods for producing intermediate compounds of formulas (3), (5) and (6) as defined in the description.

Flow microwave technology and microreactors in synthesis

A bespoke microwave reactor with a glass containment cell has been developed for performing continuous flow reactions under microwave heating. The prototype unit has been evaluated using a series of standard organic chemical transformations enabling scale-up of these chemical processes. As part of the development, a carbon-doped PTFE reactor insert was utilized to allow the heating of poorly absorbing reaction media, increasing the range of solvents and scope of reactions that can be performed in the device.