15814-76-3

Basic information

• Product Name: 5-chloro-2-(1H-pyrrol-1-yl)aniline
• Synonyms: 5-chloro-2-(1H-pyrrol-1-yl)aniline;5-Chloro-2-pyrrol-1-yl-phenylamine
• CAS NO: 15814-76-3
• Molecular Formula: C₁₀H₉ClN₂
• Molecular Weight: 192.64486
• Mol File: 15814-76-3.mol
• Article Data: 25

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-chloro-2-(1H-pyrrol-1-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(1H-pyrrol-1-yl)aniline(15814-76-3)
• EPA Substance Registry System: 5-chloro-2-(1H-pyrrol-1-yl)aniline(15814-76-3)

Safety Data

• Hazardous Substances Data: 15814-76-3(Hazardous Substances Data)

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 89-63-4 4-Chloro-2-nitroaniline 
• 1635-61-6 5-chloro-2-nitroaniline 
• 106-47-8 4-chloro-aniline 
• 539-03-7 N-(4-chlorophenyl)acetamide 
• 881-51-6 N-(4-chloro-2-nitrophenyl)-acetamide 
• 64-17-5 ethanol 
• 15893-38-6 1-(4-chloro-2-nitrophenyl)-1H-pyrrole 
• 109-97-7 pyrrole 
• 6828-35-9 5-chloro-2-iodoaniline 

Downstream Products

• 15814-74-1 7-chloro-4-phenylpyrrolo[1,2-a]quinoxaline 
• 1259379-26-4 C₂₃H₁₉ClN₄O 
• 1620494-88-3 2,2,2-trichloro-N-[5-chloro-2-(1H-pyrrol-1-yl)phenyl]acetamide 
• 1193381-85-9 C₁₃H₁₁ClN₂O 
• 99472-61-4 2-chloro-N-(5-chloro-2-pyrrol-1-ylphenyl)acetamide 

Relevant articles and documents

N,N-Dimethylformamide as Carbon Synthons for the Synthesis ofN-Heterocycles: Pyrrolo/Indolo[1,2-a]quinoxalines and Quinazolin-4-ones

N,N-dimethylformamide (DMF) as synthetic precursors contributing especially the methyl, acyl, and amino groups has played a significant role in heterocycle syntheses and functionalization. In this protocol, a wide range of pyrrolo/indolo[1,2-a]quinoxalines and quinazolin-4-ones were obtained in moderate to good yields by using elemental iodine without any metal or peroxides. We considered thatN-methyl andN-acyl of DMF participate and complete the reaction separately through different mechanisms, which displayed potential still to be explored of DMF.

Simple and green synthesis of benzimidazoles and pyrrolo[1,2-: A] quinoxalines via Mamedov heterocycle rearrangement

A method for the synthesis of coupling compounds of benzimidazoles and pyrrolo[1,2-a]quinoxalines via Mamedov Heterocycle Rearrangement is reported here. This method was conducted at room temperature and only solvent (HOAc) was required. A series of 4-(1H-benzo[d]imidazol-2-yl)pyrrolo[1,2-a]quinoxaline derivatives were obtained in moderate to good yields.

Synthesis of oxazolidinones through ring-opening and annulation of vinylene carbonate with 2-pyrrolyl/indolylanilines under Rh(iii) catalysis

Herein, we have developed a rhodium-catalyzed C-H functionalization and subsequent intramolecular ring-opening/cyclization of vinylene carbonate with 2-pyrrolyl/indolylanilines, which leads to oxazolidinones in moderate to good yields. In this transformation, vinylene carbonate only eliminates one oxygen atom rather than -CO3 or CO2. Furthermore, some control experiments are conducted to elucidate the reaction mechanism. This journal is