15868-29-8 Usage
Derivative of isochromene
Aromatic organic compound
1-Oxo-1H-isochromene-4-carboxylic acid is derived from isochromene, which is an aromatic organic compound. This means that the compound has a stable, conjugated system of double bonds and exhibits a distinctive aroma.
Class of compound
Carboxylic acids
This chemical compound belongs to the class of carboxylic acids, which are organic compounds containing a carboxyl group (-COOH). The presence of this functional group imparts acidic properties to the molecule.
Unique structure and reactivity
Potential applications in organic synthesis and pharmaceutical research
The unique structure and reactivity of 1-oxo-1H-isochromene-4-carboxylic acid make it a valuable compound for research in organic synthesis and pharmaceuticals. Its distinct properties may allow for the development of new synthetic methods and the creation of novel compounds.
Building block in synthesis
Pharmaceutical and organic compounds
1-Oxo-1H-isochromene-4-carboxylic acid can be used as a building block in the synthesis of various pharmaceuticals and other organic compounds. This makes it an important intermediate in the production of a wide range of chemical products.
Importance in chemistry and related industries
Potential usage in various fields
As an important chemical compound with a unique structure and reactivity, 1-oxo-1H-isochromene-4-carboxylic acid has potential applications in various fields of chemistry and related industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 15868-29-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,8,6 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15868-29:
(7*1)+(6*5)+(5*8)+(4*6)+(3*8)+(2*2)+(1*9)=138
138 % 10 = 8
So 15868-29-8 is a valid CAS Registry Number.
15868-29-8Relevant articles and documents
Syntheses of Fluorescent Dyes, 11. - Rearrangement of Alkoxymethylene- and Aminomethylenehomophthalic Anhydrides into Isocoumarins and Isoquinolinones, resp.
Wolfbeis, Otto S.
, p. 819 - 827 (2007/10/02)
Homophthalic acid (1) and its anhydride (3,4-dihydro-1H-2-benzopyran-1,3-dione, 2) react with trimethoxymethane in acetic acid anhydride to give 4-methoxymethylenehomophthalic anhydride (3a).This is converted into the enamines 4a-i by reaction with primary or secondary amines and ureas, respectively. 4b,d-i may also be obtained directly from 2 by reaction with a mixture of trimethoxymethane and the corresponding amine (or urea).In alkaline methanol 3a and similarly 4h suffer ring opening to give 5 and 6, respectively. - Treatment of 3a with aqueous sodium hydroxide and subsequent acidification furnishes by a rearrangement reaction the isocoumarin-4-carboxylic acid (7a) together with some of its decarboxylation product 7b, probably via an open ring intermediate of type A.Better yields of 7a are obtained by rearrangement performed in concentrated hydrochloric acid. - Similarly, compounds 4 rearrange to form the isoquinoline-4-carboxylic acids 8a-d. - Starting from homophthalic acid (1), these rearrangements offer a straightforward route to obtain fluorescent isocoumarin as well as isoquinolinone derivatives.
