15970-40-8

Basic information

• Product Name: 4-PHENYL-1H-IMIDAZOLE-1,2-DIAMINE
• Synonyms: Imidazole,1,2-diamino-4-phenyl- (8CI); 1,2-Diamino-4-phenylimidazole
• CAS NO: 15970-40-8
• Molecular Formula: C₉H₁₀N₄
• Molecular Weight: 174.21
• Mol File: 15970-40-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 456.6°C at 760 mmHg
• Flash Point: 229.9°C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 1.6E-08mmHg at 25°C
• Refractive Index: 1.695
• PKA: 5.70±0.10(Predicted)
• CAS DataBase Reference: 4-PHENYL-1H-IMIDAZOLE-1,2-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYL-1H-IMIDAZOLE-1,2-DIAMINE(15970-40-8)
• EPA Substance Registry System: 4-PHENYL-1H-IMIDAZOLE-1,2-DIAMINE(15970-40-8)

Safety Data

• Hazardous Substances Data: 15970-40-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10N4/c10-9-12-8(6-13(9)11)7-4-2-1-3-5-7/h1-6H,11H2,(H2,10,12)

Upstream product

• 15970-04-4 N-(2-amino-4-phenyl-1H-imidazol-1-yl)acetamide 
• 185422-40-6 2-amino-1-(3-nitrobenzylidene)-4-phenylimidazole 

Downstream Products

• 85510-55-0 2,8-Diphenyl-6-p-tolyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 85510-64-1 8-(4-Chloro-phenyl)-2,6-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 85510-59-4 6-(4-Nitro-phenyl)-2,8-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 85510-58-3 6-(4-Bromo-phenyl)-2,8-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 85780-27-4 5-[(Z)-2-Amino-4-phenyl-imidazol-1-ylimino]-1,1,2,2-tetrafluoro-hexan-3-one 
• 85510-63-0 8-(4-Methoxy-phenyl)-2,6-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 54221-50-0 2,4-dimethyl-5-phenylimidazo[1,5-b]pyridazin-7-ylamine 
• 440339-04-8 2-amino-1-isopropylideneamino-4-phenyl-1H-imidazole 
• 28734-00-1 2-amino-1-benzylideneamino-4-phenyl-1H-imidazole 
• 1222-98-6 4-nitrochalcone 
• 25870-67-1 1,3-bis(4-nitrophenyl)prop-2-en-1-one 
• 85510-56-1 6-(4-Methoxy-phenyl)-2,8-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 
• 85510-57-2 6-(4-Chloro-phenyl)-2,8-diphenyl-8,9-dihydro-7H-imidazo[1,2-b][1,2,4]triazepine 

Relevant articles and documents

New Iridium Catalysts for the Selective Alkylation of Amines by Alcohols under Mild Conditions and for the Synthesis of Quinolines by Acceptor-less Dehydrogenative Condensation

A novel family of iridium catalysts stabilised by P,N-ligands have been introduced. The ligands are based on imidazo[1,5-b]pyridazin-7-amines and can be synthesised with a broad variety of substitution patterns. The catalysts were synthesised quantitatively from the protonated ligands and a commercially available iridium precursor. The catalysts mediate the alkylation of amines by alcohols under mild conditions (70 °C). In addition, the synthesis of quinolines from secondary or primary alcohols and amino alcohols is reported. This sustainable synthesis proceeds through the liberation of two equivalents of water and two equivalents of dihydrogen. The investigations indicate that catalysts suitable for hydrogen autotransfer or borrowing hydrogen chemistry might also be suitable for acceptor-less dehydrogenative condensation reactions. Your H or mine? A family of catalysts that mediate the alkylation of amines by alcohols under mild conditions are introduced (see scheme; HA=hydrogen autotransfer, BH=borrowing hydrogen, ADC=acceptor-less dehydrogenative condensation). The efficient synthesis of quinolines from alcohols and amino alcohols through the liberation of two equivalents of dihydrogen is also mediated by this catalyst family.

Method for inhibiting advanced glycosylation of proteins using aminosubstituted imidazoles

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging), Accordingly, a composition is disclosed which comprises 2-aminoimidazoles capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation, The method comprises contacting the target protein with the composition, Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.