160332-17-2Relevant articles and documents
Nucleophilic reactions between cyclic 1,2-sulfites and chloride ions
Nymann, Kirsten,Jensen, Linda,Svendsen, John S.
, p. 832 - 841 (2007/10/03)
When cyclic 1,2-sulfites are ring opened by chloride ion, the chlorohydrins are formed with low regio- and stereo-selectivity. The mechanisms involved in the process were investigated by measuring the stereochemical outcome of the reactions. The results showed that reversible inversion pathways (SN2 reactions) and a retention pathway (SN2i reaction) gave rise to the loss in ee in both the chlorohydrins and in the cyclic 1,2-sulfites. Acta Chemica Scandinavica 1996.