160682-93-9

Basic information

• Product Name: 1,1-Bis-(4-fluoro-phenyl)-2-(1S,9aR)-octahydro-quinolizin-1-yl-ethanol
• CAS NO: 160682-93-9
• Molecular Weight: 371.47
• Mol File: 160682-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1-Bis-(4-fluoro-phenyl)-2-(1S,9aR)-octahydro-quinolizin-1-yl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Bis-(4-fluoro-phenyl)-2-(1S,9aR)-octahydro-quinolizin-1-yl-ethanol(160682-93-9)
• EPA Substance Registry System: 1,1-Bis-(4-fluoro-phenyl)-2-(1S,9aR)-octahydro-quinolizin-1-yl-ethanol(160682-93-9)

Safety Data

• Hazardous Substances Data: 160682-93-9(Hazardous Substances Data)

Upstream product

• 23506-89-0 (1S,9aR)-1-(aminomethyl)-(octahydro-2H-quinolizine) 
• 345-92-6 4,4'-Difluorobenzophenone 

Downstream Products

• 160682-98-4 (1S,9aR)-1-[2,2-Bis-(4-fluoro-phenyl)-vinyl]-octahydro-quinolizine 

Relevant articles and documents

Quinolizidine derivatives with antitubercular activity

By reacting lupinylmagnesium chloride with suitable aromatic ketones, several lupinyldiarylcarbinols were obtained, whose dehydration gave the corresponding lupinylidenediarylmethanes. By reduction of three of these unsaturated compounds, the corresponding lupinyldiarylmethanes were also obtained. Direct condensation of lupinine with fluorene gave the 9-epi- lupinylfluorene. The quinolizidine derivatives obtained were tested against Mycobacterium tuberculosis H37RV. Nine compounds resulted endowed with good antitubercular activity with MIC 0.1 0.5 μg/ml.