1609281-86-8

Basic information

• Product Name: AZD3264
• Synonyms: AZD3264
• CAS NO: 1609281-86-8
• Molecular Formula: C21H23N5O4S
• Molecular Weight: 441.50342
• EINECS: -0
• Mol File: 1609281-86-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 614.2±55.0 °C(Predicted)
• Appearance: /
• Density: 1.371±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 13.16±0.50(Predicted)
• CAS DataBase Reference: AZD3264(CAS DataBase Reference)
• NIST Chemistry Reference: AZD3264(1609281-86-8)
• EPA Substance Registry System: AZD3264(1609281-86-8)

Safety Data

• Hazardous Substances Data: 1609281-86-8(Hazardous Substances Data)

Usage

Uses

AZD 3264 is a scalable IKK2 Inhibitor .

Upstream product

• 354812-10-5 2-[(aminocarbonyl)amino]-5-bromo-3-thiophenecarboxamide 
• 1609116-60-0 C₂₆H₃₇BN₂O₆ 
• 1609116-59-7 [2-[(3S)-1-tert-butoxycarbonylpyrrolidin-3-yl]oxy-4-(3,5-dimethylisoxazol-4-yl)phenyl]boronic acid 
• 1609116-50-8 tert-butyl (3S)-3-[2-bromo-5-(3,5-dimethylisoxazol-4-yl)phenoxy]pyrrolidine-1-carboxylate 
• 1609116-58-6 C₁₅H₁₉BrINO₃ 
• 1609116-57-5 C₁₅H₁₉Br₂NO₃ 
• 1609116-56-4 tert-butyl(3S)-3-[2-(4-carbamoyl-5-ureido-2-thienyl)-5-(3,5-dimethylisoxazol-4-yl)phenoxy]pyrrolidine-1-carboxylate 
• 1609116-54-2 C₁₅H₂₁BClNO₅ 
• 1609116-53-1 C₁₅H₁₉BrClNO₃ 
• 136434-77-0 4-bromo-3-fluoroiodobenzene 
• 1435-52-5 2,5-dibromofluorobenzene 
• 1996-29-8 1-bromo-4-chloro-2-fluorobenzene 

Relevant articles and documents

Exploiting the differential reactivities of halogen atoms: Development of a scalable route to IKK2 inhibitor AZD3264

An efficient and scalable synthesis of AZD3264 is described in which the differential reactivities of various halogen atoms have been employed. The process involves five linear chemical steps with three isolated stages starting from commercially available fragments.