1610460-62-2

Basic information

• Product Name: C₂₄H₃₃NO₇S
• Synonyms: C₂₄H₃₃NO₇S
• CAS NO: 1610460-62-2
• Molecular Weight: 479.595
• Mol File: 1610460-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₃₃NO₇S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₃NO₇S(1610460-62-2)
• EPA Substance Registry System: C₂₄H₃₃NO₇S(1610460-62-2)

Safety Data

• Hazardous Substances Data: 1610460-62-2(Hazardous Substances Data)

Upstream product

• 694-05-3 1,2,3,6-tetrahydropyridine 
• 161157-50-2 tert-butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 1067-74-9 Methyl diethylphosphonoacetate 
• 1610460-60-0 tert-butyl-4-[(2-(3-methoxyphenyl)-1,3-dioxolan-2-yl)methylsulfanyl]-3-oxopiperidine-1-carboxylate 
• 1610460-56-4 1-((2-(3-methoxyphenyl)-1,3-dioxolan-2-yl)methylsulfanyl)ethan-1-one 
• 1610460-57-5 2-(3-methoxyphenyl)-1,3-dioxolanylmethanethiol 
• 175657-38-2 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Synthesis of the stabilized active metabolite of clopidogrel

The convergent synthesis of the stabilized active metabolite of clopidogrel was achieved in eleven steps from commercially available 1,2,3,6- tetrahydropyridine and 2-bromo-3′-methoxy acetophenone (MPBr). This synthetic route used a standard Horner-Wadsworth-Emmons reaction allowing the introduction of a Z exocyclic double bond. A selective hydrolysis of an acrylic methyl ester moiety, isolated by an efficient and reliable preparative chiral chromatography at gram scale, released the title compound with a 98% LC purity and d.e. >99%.