175657-38-2

Basic information

• Product Name: 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one
• Synonyms: 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one
• CAS NO: 175657-38-2
• Molecular Weight: 224.28
• Mol File: 175657-38-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one(175657-38-2)
• EPA Substance Registry System: 2-(acetylsulfanyl)-1-(3-methoxyphenyl)ethan-1-one(175657-38-2)

Safety Data

• Hazardous Substances Data: 175657-38-2(Hazardous Substances Data)

Upstream product

• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 10387-40-3 potassium thioacetate 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 507-09-5 tiolacetic acid 

Downstream Products

• 1610460-57-5 2-(3-methoxyphenyl)-1,3-dioxolanylmethanethiol 
• 1610460-60-0 tert-butyl-4-[(2-(3-methoxyphenyl)-1,3-dioxolan-2-yl)methylsulfanyl]-3-oxopiperidine-1-carboxylate 
• 1610460-61-1 tert-butyl (Z)-3-(2-methoxy-2-oxoethylidene)-4-[(2-(3-methoxyphenyl)-1,3-dioxolan-2-yl)methylsulfanyl]piperidine-1-carboxylate 
• 1610460-62-2 C₂₄H₃₃NO₇S 
• 1610460-64-4 methyl (2S,3Z)-2-(2-chlorophenyl)-2-[3-(2-methoxy-2-oxoethylidene)-4-((2-(3-methoxyphenyl)-2-oxoethyl)sulfanyl)piperidin-1-yl]acetate 
• 1610460-65-5 methyl (2S,3Z)-2-(2-chlorophenyl)-2-[3-(2-methoxy-2-oxoethylidene)-4-((2-(3-methoxyphenyl)-2-oxoethyl)sulfanyl)piperidin-1-yl]acetate 
• 1430373-14-0 2-(((3Z,4R)-1-((S)-1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-(2-(3-methoxyphenyl)-2-oxoethyl)sulfanyl)piperidin-3-ylidene)acetic acid 
• 1610460-63-3 C₁₇H₂₁NO₄S 
• 1610460-56-4 1-((2-(3-methoxyphenyl)-1,3-dioxolan-2-yl)methylsulfanyl)ethan-1-one 
• 175657-51-9 4-Hydroxy-5-(3-methoxy-benzoyl)-thiophene-2-carboxylic acid 
• 175657-44-0 4-Hydroxy-5-(3-methoxy-benzoyl)-thiophene-2-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis of the stabilized active metabolite of clopidogrel

The convergent synthesis of the stabilized active metabolite of clopidogrel was achieved in eleven steps from commercially available 1,2,3,6- tetrahydropyridine and 2-bromo-3′-methoxy acetophenone (MPBr). This synthetic route used a standard Horner-Wadsworth-Emmons reaction allowing the introduction of a Z exocyclic double bond. A selective hydrolysis of an acrylic methyl ester moiety, isolated by an efficient and reliable preparative chiral chromatography at gram scale, released the title compound with a 98% LC purity and d.e. >99%.