16106-44-8

Basic information

• Product Name: potassium toluene-4-sulphonate
• Synonyms: potassium toluene-4-sulphonate;p-Toluenesulfonic acid, potassium salt;Benzenesulfonic acid, 4-methyl-, potassium salt;TOLUENESULFONATE,POTASSIUMSALT;TOLUENESULFONICACID,POTASSIUMSALT;4-methyl-benzenesulfonic aci potassium salt;Potassium p-toluenesulfonate;4-Toluenesulfonic acid potassium salt
• CAS NO: 16106-44-8
• Molecular Formula: C₇H₇O₃S*K
• Molecular Weight: 210.29198
• EINECS: 240-273-5
• Mol File: 16106-44-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.34g/cm³
• CAS DataBase Reference: potassium toluene-4-sulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: potassium toluene-4-sulphonate(16106-44-8)
• EPA Substance Registry System: potassium toluene-4-sulphonate(16106-44-8)

Safety Data

• Hazardous Substances Data: 16106-44-8(Hazardous Substances Data)

Usage

General Description

Potassium toluene-4-sulphonate, also known as potassium p-toluenesulfonate, is a white crystalline powder with the chemical formula C7H7KO3S. It is a versatile chemical compound that is commonly used as a catalyst in various organic reactions, such as the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also used as an additive in electroplating and as a stabilizer in the production of various polymers. Additionally, potassium toluene-4-sulphonate is utilized in the manufacturing of cosmetics and personal care products, as well as in the pharmaceutical industry for the production of various drugs and medications. Its water-solubility and stability make it a valuable chemical in various industrial and commercial applications.

InChI:InChI=1/C7H8O3S.K/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);/q;+1/p-1

Upstream product

• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 3900-79-6 toluene-4-sulfonic acid isopropylidenehydrazide 
• 65288-11-1 3-(phenylsulfonyl)propyl p-toluenesulfonate 
• 31367-69-8 potassium p-tolylthiolate 
• 104-15-4 toluene-4-sulfonic acid 
• 75230-50-1 p-chloroacetophenone tosylhydrazone 
• 80-48-8 methyl p-toluene sulfonate 
• 89690-47-1 potassium 3,4-dichlorobenzenesulfonate 
• 105355-27-9 Pioglitazone 
• 144809-27-8 toluene-4-sulfonic acid 2-(5-ethylpyridin-2-yl)ethyl ester 
• 82745-72-0 2-(((4-methylphenyl)sulfonyl)oxy)benzoic acid 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 113965-52-9 N'-(1,1-diphenylpropan-2-ylidene)-4-methylbenzenesulfonohydrazide 
• 19350-71-1 N'-(3-methoxybenzylidene)-4-methylbenzenesulfonohydrazide 

Downstream Products

• 162253-63-6 S-2,4-dichlorobenzyl thiotosylate 
• 13079-28-2 benzoic toluene-p-sulphonic anhydride 
• 1192478-71-9 C₇H₇O₃S^(1-)*C₂₁H₄₆N₆P⁽¹⁺⁾ 
• 1192478-75-3 C₇H₇O₃S^(1-)*C₂₂H₄₀N₅⁽¹⁺⁾ 
• 455-16-3 p-toluenesulfonyl fluoride 
• 80-48-8 methyl p-toluene sulfonate 
• 1678-43-9 1-benzoyl-1-phenylmethyl p-toluenesulfonate 
• 93435-57-5 α-tosyloxy-p-methoxyacetophenone 
• 81447-33-8 toluene-4-sulfonic acid 1-methyl-2-oxobutyl ester 
• 16836-95-6 silver(I) 4-methylbenzenesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 98029-44-8 N-butylpyridine p-toluenesulfonate 
• 89690-47-1 potassium 3,4-dichlorobenzenesulfonate 

Relevant articles and documents

FACILE CONVERSION OF TOSYLHYDRAZONES TO THE CARBONYL COMPOUNDS USING PEROXYSULFUR INTERMEDIATE

Various tosylhydrazones, such as dialkyl and aryl-alkyl tosylhydrazones, were found to react with a peroxysulfur intermediate, which was generated by the reaction of 2-nitrobenzenesulfonyl chloride with superoxide, to be converted into the corresponding carbonyl compounds, in mostly quantitative yields, at -30 deg C under mild conditions.

Pioglitazone impurities

Methods of preparation of API pioglitazone were discussed from the point of view of impurities occurrence. Four real impurities (I-IV) of pioglitazone were prepared and characterized by means of NMR spectroscopy.

Generation of Benzyne in the Thermal Decomposition of 2-Carboxyphenyl p-Toluenesulfonate

The scope and the mechanism of the generation of 1,2-dehydrobenzene in the thermal decomposition of 2-carboxyphenyl p-toluenesulfonate and its salts (3) have been studied. 1,2-Dehydrobenzene, which can be trapped with dienic or nucleophilic reagents, is formed in a nonconcerted process with the intermediacy of a species C6H4CO2 (11) (probably benzoxet-2-one).A complex mixture of disalicylide, trisalicylide, and some other polysalicylides is formed, in the absence of trapping agents, by polymerization of this intermediate.