16107-87-2

Basic information

• Product Name: 6-methyl-2,3-di-p-tolylquinoxaline
• Synonyms: 6-methyl-2,3-di-p-tolylquinoxaline
• CAS NO: 16107-87-2
• Molecular Weight: 324.425
• Mol File: 16107-87-2.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 6-methyl-2,3-di-p-tolylquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2,3-di-p-tolylquinoxaline(16107-87-2)
• EPA Substance Registry System: 6-methyl-2,3-di-p-tolylquinoxaline(16107-87-2)

Safety Data

• Hazardous Substances Data: 16107-87-2(Hazardous Substances Data)

Upstream product

• 5173-28-4 1,2-di-p-tolylethane-1,2-diol 
• 89-62-3 4-methyl-2-nitroaniline 
• 496-72-0 4-methyl-1,2-diaminobenzene 
• 1218-89-9 4,4'-dimethylbenzoin 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 

Relevant articles and documents

Room temperature facile synthesis of quinoxalines catalyzed by amidosulfonic acid

(Chemical Equation Presented) Amidosulfonic acid NH2-SO 3H catalyzed direct condensations of o-phenylenediamines with α-diketones at room temperature in organic solvents to afford quinoxalines in excellent yields. The amidosulfonic acid as a solid acid catalyst in this preparation was efficient and recoverable.

In water organic synthesis: Introducing itaconic acid as a recyclable acidic promoter for efficient and scalable synthesis of quinoxaline derivatives at room temperature

Substituted quinoxaline derivatives are traditionally synthesized by co-condensation of various starting materials. Herein, we describe a novel environmentally benign in water synthetic route for the synthesis of structurally and electronically diverse ninety quinoxalines with readily available substituted o-phenylenediamine and 1,2-diketones using cheap and biodegradable itaconic acid as a mild acid promotor in 1 hours. The reaction is performed at room temperature, which proceeds through cyclo-condensation reaction followed by obtaining the aforesaid nitrogen-containing heterocyclic adducts without performing the column chromatography up to 96% total yields. The simplicity, high efficiency, and reusable of the catalyst merits this reaction condition as “green synthesis” which enables it to be useful in synthetic transformations upto gram scale level.

A green solid acid catalyst 12-tungstophosphoric acid H3[PW12O40] supported on g-C3N4 for synthesis of quinoxalines

A green Keggin-type heteropoly-12-tungstophosphoric acid, (H3[PW12O40].12H2O) supported on graphitic carbon nitride g-C3N4 (HPW/g-C3N4-40), was developed for one-pot s