1218-89-9

Basic information

• Product Name: 4,4'-DIMETHYLBENZOIN
• Synonyms: 4,4'-DIMETHYLBENZOIN;Dimethylbenzoin;4,4'-Dimethylbenzoin 98%;4,4''-DIMETHYLBENZOIN 98+%;Toluoin;1,2-Bis(4-methylphenyl)-2-hydroxyethanone;2-Hydroxy-1,2-bis(4-methylphenyl)ethanone;p-Toluoin
• CAS NO: 1218-89-9
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.3
• Product Categories: Benzhydrols, Benzyl & Special Alcohols;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 1218-89-9.mol
• Article Data: 69

Chemical Properties

• Melting Point: 88°C
• Boiling Point: 210 °C / 1mmHg
• Flash Point: 170.5°C
• Appearance: /
• Density: 1.13g/cm³
• PKA: 12.16±0.20(Predicted)
• CAS DataBase Reference: 4,4'-DIMETHYLBENZOIN(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIMETHYLBENZOIN(1218-89-9)
• EPA Substance Registry System: 4,4'-DIMETHYLBENZOIN(1218-89-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 1218-89-9(Hazardous Substances Data)

Usage

General Description

4,4'-Dimethylbenzoin is a chemical compound that belongs to the family of benzoin compounds, which are widely used as photoinitiators in photopolymerization processes. It consists of two benzene rings with two methyl groups attached at the 4th position of each ring. 4,4'-DIMETHYLBENZOIN is a white to pale yellow crystalline powder and is sparingly soluble in water but soluble in organic solvents. 4,4'-Dimethylbenzoin is used as a photoinitiator in the production of adhesives, coatings, and inks, and it helps to initiate the polymerization reaction when exposed to UV light. Its low volatility and high reactivity make it a valuable component in the production of various polymer materials. Additionally, it is also used in the synthesis of other chemical compounds.

Upstream product

• 64-17-5 ethanol 
• 151-50-8 potassium cyanide 
• 104-87-0 4-methyl-benzaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 108-88-3 toluene 
• 60-29-7 diethyl ether 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 30615-54-4 triphenylmethyl bromide 
• 589-18-4 4-Methylbenzyl alcohol 
• 140-88-5 ethyl acrylate 
• 107-13-1 acrylonitrile 
• 5173-28-4 (1R,2S)-1,2-Di-p-tolyl-ethane-1,2-diol 
• 78-94-4 methyl vinyl ketone 
• 111098-80-7 bis(benzotriazolo)(4-methylphenyl)methane 

Downstream Products

• 116238-58-5 4,5-bis-(4-methylphenyl)-1H-imidazole 
• 860185-17-7 1,2,7,8-Tetra-p-tolyl-benzo[1,2-b;4,3-b']difuran 
• 860185-16-6 2,3,6,7-Tetra-p-tolyl-benzo[1,2-b;4,5-b']difuran 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 97740-20-0 3,4-di-p-tolyl-2,3-dihydro-[1,2,5]thiadiazole 1,1-dioxide 
• 38305-61-2 2,5-diphenyl-3,4-di(p-tolyl)cyclopenta-2,4-dien-1-one 
• 119267-75-3 2-oxo-1,2-di(p-tolyl)ethyl acetate 
• 40352-55-4 4,5-di-p-tolyl-[1,3]dioxol-2-one 
• 99-94-5 p-Toluic acid 
• 13222-85-0 p-methylbenzoic anhydride 
• 99648-36-9 1,3,6,8-tetrakis(4-methylphenyl)-2,4,5,7,9,10-hexaoxatricyclo<6.2.0.0^3,6>decane 
• 1362857-41-7 1-(2?methyl?4,5?di(p?tolyl)?1H?pyrrole?3?yl)?ethanone 
• 16112-21-3 2-(4-methylphenyl)-1,3-benzothiazole 
• 50373-76-7 5,5-bis(4-methylphenyl)imidazolidine-2,4-dione 

Relevant articles and documents

Efficient and mild benzoin condensation reaction catalyzed by simple 1-N-alkyl-3-methylimidazolium salts

The benzoin reaction, catalyzed by simple 1-N-alkyl-3-methylimidazolium salt-based ionic liquid via carbene intermediate, to give the α-hydroxyl ketone proceeds in CH2Cl2 under mild conditions.

A new protocol for one-pot synthesis of tetrasubstituted pyrroles using tungstate sulfuric acid as a reusable solid catalyst

A variety of tetrasubstituted pyrroles were synthesized in good yields in a one-pot, three-component reaction of α-hydroxyketones, malononitrile, and ammonium acetate using tungstate sulfuric acid (TSA) under solvent-free conditions.

Organocatalytic Synthesis of Substituted Vinylene Carbonates

The organocatalytic synthesis of substituted vinylene carbonates from benzoins and acyloins was studied using diphenyl carbonate as a carbonyl source. A range of N-Heterocyclic Carbene (NHC) precursors were screened and it was found that imidazolium salts were the most active for this transformation. The reaction occurs at 90 °C under solvent-free conditions. A wide range of substituted vinylene carbonates (symmetrical and unsymmetrical, aromatic or aliphatic), including some derived from natural products, were prepared with 20–99% isolated yields (24 examples). The reaction was also developed using thermomorphic polyethylene-supported organocatalysts as recoverable and recyclable species. The use of such species facilitates the workup and allows the synthesis of vinylene carbonates on the preparative scale (>30 g after 5 runs). (Figure presented.).

1-butyl-3-methylimidazolium bromide as a solvent and precatalyst for stetter reaction

Stetter reaction between aromatic aldehydes and acrylonitrile/ethyl acrylate performing in [Bmim]Br in the presence of NaOH is described. N-Heterocyclic carbene (NHC) generates in situ is shown to be an efficient catalyst. Benzoin condensation also occured as side reaction.