16112-22-4

Basic information

• Product Name: 2-(4-methylphenyl)-5-phenylthiazole
• Synonyms: 2-(4-methylphenyl)-5-phenylthiazole
• CAS NO: 16112-22-4
• Molecular Weight: 251.352
• Mol File: 16112-22-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-methylphenyl)-5-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methylphenyl)-5-phenylthiazole(16112-22-4)
• EPA Substance Registry System: 2-(4-methylphenyl)-5-phenylthiazole(16112-22-4)

Safety Data

• Hazardous Substances Data: 16112-22-4(Hazardous Substances Data)

Upstream product

• 122-78-1 phenylacetaldehyde 
• 104-84-7 para-methylbenzylamine 
• 27088-83-1 2-(4-Methylphenyl)thiazole 
• 591-50-4 iodobenzene 
• 1826-13-7 5-phenylthiazole 
• 624-31-7 4-tolyl iodide 
• 82221-14-5 4-Methyl-N-[1-(2-oxo-2-phenylethyl)]benzamide 

Downstream Products

• 52659-00-4 2-{4-[4-(5-phenyl-thiazol-2-yl)-trans-styryl]-phenyl}-2H-naphtho[1,2-d][1,2,3]triazole 
• 52822-16-9 2-[4-(trans-2-dibenzofuran-3-yl-vinyl)-phenyl]-5-phenyl-thiazole 
• 16178-37-3 2-[4-(trans-2-biphenyl-4-yl-vinyl)-phenyl]-5-phenyl-thiazole 
• 16178-36-2 5-phenyl-2-(4-trans-styryl-phenyl)-thiazole 

Relevant articles and documents

Cu-Catalyzed Aerobic Oxidative Sulfuration/Annulation Approach to Thiazoles via Multiple Csp3-H Bond Cleavage

A novel and practical Cu-catalyzed aerobic oxidative synthesis of thiazoles was developed. This chemistry for the first time achieved thiazole construction from simple aldehydes, amines, and element sulfur through multiple Csp3-H bond cleavage processes. Molecular oxygen was used as a green oxidant in this oxidative protocol. The substrate scope is broad with the tolerance of aliphatic amines. The mechanistic study might promote the reaction design for a new sulfuration/annulation reaction with readily available element sulfur.

Pd nanoparticle-silica nanotubes (Pd@SNTs) as an efficient catalyst for Suzuki-Miyaura coupling and sp2 C-H arylation in water

Silica nanotubes (SNTs) functionalized with Pd-NPs on the inner surface performed as efficient nano-reactors for C-C coupling in water; the nano-confinement offers minimized leaching of Pd and yet efficient mass transfer for Suzuki-Miyaura coupling and C-H arylation of thiazoles in water with very high TON.