1612898-21-1Relevant articles and documents
New indolylarylsulfones as highly potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors
Famiglini, Valeria,La Regina, Giuseppe,Coluccia, Antonio,Pelliccia, Sveva,Brancale, Andrea,Maga, Giovanni,Crespan, Emmanuele,Badia, Roger,Clotet, Bonaventura,Esté, José A.,Cirilli, Roberto,Novellino, Ettore,Silvestri, Romano
, p. 101 - 111 (2014/05/06)
New indolylarylsulfone HIV-1 NNRTIs were synthesized to evaluate unexplored substitutions of the benzyl/phenylethyl group linked at the indole-2-carboxamide. Against the NL4-3 HIV-1 WT strain, 17 out 20 compounds were superior to NVP and EFV. Several comp