161878-82-6

Basic information

• Product Name: (S)-4-((S)-2-tert-Butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid tert-butyl ester
• Synonyms: (S)-4-((S)-2-tert-Butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid tert-butyl ester
• CAS NO: 161878-82-6
• Molecular Weight: 731.89
• Mol File: 161878-82-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-((S)-2-tert-Butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-((S)-2-tert-Butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid tert-butyl ester(161878-82-6)
• EPA Substance Registry System: (S)-4-((S)-2-tert-Butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-2-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyric acid tert-butyl ester(161878-82-6)

Safety Data

• Hazardous Substances Data: 161878-82-6(Hazardous Substances Data)

Upstream product

• 161878-68-8 (S)-2-Benzyloxycarbonylamino-4-((S)-2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-butyric acid tert-butyl ester 
• 112888-77-4 tert-butyl 4--N-prop-2-ynylamino>benzoate 
• 112888-76-3 tert-butyl p-[N-(prop-2-ynyl)amino]benzoate 
• 112888-43-4 4(3H)-oxo-6-(bromomethyl)-2-methyl quinazoline 
• 48067-24-9 O-tert-butyl L-serine tert-butyl ester 
• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 
• 138899-84-0 4--N-prop-2-ynylamino>benzoic acid, trifluoroacetate salt 
• 1054629-82-1 (S)-2-Amino-4-((S)-2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-butyric acid tert-butyl ester 

Relevant articles and documents

The Synthesis and Thymidylate Synthase Inhibitory Activity of L-γ-L-Linked Dipeptide and L-γ-Amide Analogues of 2-Desamino-2-methyl-N10-propargyl-5,8-dideazafolic Acid (ICI 198583)

Sixteen γ-linked dipeptide and four L-Glu-γ-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) have beensynthesized and evaluated as inhibitors of thymidylate synthase (TS).Z-blocked L-Glu-γ-L-linked dipepti