1621107-03-6

Basic information

• Product Name: methyl 2-((4-fluorophenyl)(methyl)amino)benzoate
• Synonyms: methyl 2-((4-fluorophenyl)(methyl)amino)benzoate
• CAS NO: 1621107-03-6
• Molecular Weight: 259.28
• Mol File: 1621107-03-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 2-((4-fluorophenyl)(methyl)amino)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-((4-fluorophenyl)(methyl)amino)benzoate(1621107-03-6)
• EPA Substance Registry System: methyl 2-((4-fluorophenyl)(methyl)amino)benzoate(1621107-03-6)

Safety Data

• Hazardous Substances Data: 1621107-03-6(Hazardous Substances Data)

Upstream product

• 88-65-3 2-bromobenzoic-acid 
• 124-38-9 carbon dioxide 
• 403-46-3 4-fluoro-N,N-dimethylaniline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 371-40-4 4-fluoroaniline 
• 88-67-5 2-Iodobenzoic acid 
• 54-60-4 4'-fluorodiphenylamine-2-carboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 1454934-32-7 C₁₄H₁₄FNO 
• 1455315-58-8 2-((4-fluorophenyl)(methyl)amino)benzaldehyde 

Relevant articles and documents

Redox-neutral decarboxylative photocyclization of anthranilic acids

A mild metal-, catalyst-, and oxidant-free photoredox neutral system has been found to efficiently enable intramolecular decarboxylative cyclization of anthranilic acids. This facile protocol provides an alternative method for the synthesis of carbazoles. Mechanistic studies reveal a key photoinduced 6π-electrocyclization process and formic acid was released as the sole byproduct.

PhI(OAc)2-mediated intramolecular oxidative aryl-aldehyde C sp 2-C sp 2 bond formation: Metal-free synthesis of acridone derivatives

A metal-free protocol for direct aryl-aldehyde Csp2-Csp 2 bond formation via a PhI(OAc)2-mediated intramolecular cross-dehydrogenative coupling (CDC) of various 2-(N-arylamino)aldehydes was developed. The novel methodology requires no need of preactivation of the aldehyde group, is applicable to a large variety of functionalized substrates, and most of all provides a convenient approach to the construction of biologically important acridone derivatives.