162809-97-4

Basic information

• Product Name: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel
• Synonyms: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel
• CAS NO: 162809-97-4
• Molecular Weight: 1040.41
• Mol File: 162809-97-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(162809-97-4)
• EPA Substance Registry System: 2'-O-(tert-butyldimethylsilyl)-10-deacetyl-7-O-triethylsilylpaclitaxel(162809-97-4)

Safety Data

• Hazardous Substances Data: 162809-97-4(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 78432-77-6 10-deacetylpaclitaxel 
• 114655-02-6 2'-O-(tert-butyldimethylsilyl)paclitaxel 
• 33069-62-4 taxol 
• 994-30-9 triethylsilyl chloride 
• 162375-26-0 2'-O-(tert-butyldimethylsilyl)-10-deacetylpaclitaxel 

Downstream Products

• 886769-93-3 C₆₈H₁₀₁N₅O₁₄Si₂ 
• 849213-05-4 2-O-TES-7-O-methylthiomethyl-9-α-OH-10-epi-paclitaxel 
• 849213-04-3 2'-O-TES-9-α-OH-10-epi-paclitaxel 
• 849213-07-6 C₅₄H₆₇NO₁₄Si 
• 849213-06-5 7-O-methylthiomethyl-9-α-OH-10-epi-paclitaxel 
• 849213-08-7 C₄₈H₅₃NO₁₄ 
• 849342-14-9 C₆₂H₇₁NO₁₇ 
• 849213-09-8 9-desoxo-7,9-anisaldehyde acetal 10-epipaclitaxel 
• 849213-02-1 2-O-TBDMS-9,10-α,α-OH-9-desoxo-10-deacetyl-paclitaxel 
• 849213-10-1 7,9-anisaldehyde acetal-9-desoxo-10-epi-baccatin III 
• 1052091-65-2 C₆₂H₇₁NO₁₇ 

Relevant articles and documents

Syntheses of Novel C-9 and C-10 Modified Bioactive Taxanes

A method has been developed for the syntheses of hitherto unreported C-9 and C-10 modified taxanes.These analogs demonstrated excellent to good cytotoxicity against B 16 melanoma cells.

TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER

Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a s

BIOLOGICALLY ACTIVE TAXANE ANALOGS AND METHODS OF TREATMENT BY ORAL ADMINISTRATION

The present invention relates to a novel chemical compound of formula S-(I) for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.