16281-95-1

Basic information

• Product Name: 2-(1-Bromethyl)-benzoesaeuremethylester
• Synonyms: 2-(1-Bromethyl)-benzoesaeuremethylester
• CAS NO: 16281-95-1
• Molecular Weight: 243.1
• Mol File: 16281-95-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 295.4±23.0 °C(Predicted)
• Density: 1.396±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(1-Bromethyl)-benzoesaeuremethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Bromethyl)-benzoesaeuremethylester(16281-95-1)
• EPA Substance Registry System: 2-(1-Bromethyl)-benzoesaeuremethylester(16281-95-1)

Safety Data

• Hazardous Substances Data: 16281-95-1(Hazardous Substances Data)

Usage

Appearance

White solid Describes the physical form and color of the compound, which is a white solid.

Use as intermediate

Synthesis of pharmaceuticals and agrochemicals The compound serves as a starting material or building block in the production of various pharmaceutical and agrochemical products.

Importance in organic chemistry

Building block The compound is a key component in the creation of other organic compounds, making it valuable in the field of organic chemistry.

Industrial applications

Reactivity and versatility The compound's ability to react with other substances and its adaptability make it useful in various industrial processes.

Utilization in new compound development

Various industries The compound is widely used in the research and development of new chemical products for a range of industries.

Upstream product

• 76118-05-3 2-ethylbenzoyl chloride 
• 578-54-1 ortho-ethylaniline 
• 34136-59-9 o-ethylbenzonitrile 
• 118-90-1 ortho-methylbenzoic acid 
• 50604-01-8 ethyl-benzoic acid methyl ester 
• 612-19-1 2-ethylbenzoic acid 

Downstream Products

• 92552-45-9 2-phenyl-3-methylisoindolin-1-one 

Relevant articles and documents

One-pot method to construct isoindolinones and its application to the synthesis of DWP205109 and intermediate of Lenalidomide

Herein a practical and efficient system for concise synthesis of isoindolinones is described by using substituted methyl 2-(halomethyl)benzoates and substituted amines. Structurally various methyl 2-(halomethyl)benzoates and amines were transformed into isoindolinones 80–99% yield and purity in catalyst-free and solvent-free conditions. The method has a wide substrate scope. The synthetic utility of the one-pot reaction was demonstrated by the concise syntheses of Lenalidomide intermediate and DWP205190.

Fungicides

Fungicidal compounds of the formula (I): STR1 and stereoisomers thereof, wherein R1 is optionally substituted aryl or optionally substituted heteroaryl; Y is oxygen, sulphur or NR4 ; R2, R3 and R4, which may be the same or different, are hydrogen, C1-4 alkyl or C2-4 alkenyl; X is halogen, C1-4 alkyl, C2-4 alkenyl, C1-4 alkoxy, nitro or cyano; and n is 0 or an integer of 1 to 4; provided that when Y is oxygen, n is O and R1 is unsubstituted phenyl at least one of R2 and R3 is other than hydrogen or methyl.