16352-18-4 Usage
Description
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is a clear, colorless liquid with a characteristic odor and is highly flammable. It is a chemical compound primarily used as a reagent in organic synthesis and chemical research. 4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLAN-2-OL, 95% is also known for its ability to act as a chiral ligand in asymmetric catalysis, making it an important tool for producing enantiomerically pure compounds.
Uses
Used in Organic Synthesis:
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is used as a reagent in organic synthesis for the production of various organic compounds. Its versatility as a reagent makes it a valuable component in chemical research.
Used as a Solvent:
In the chemical industry, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is used as a solvent due to its ability to dissolve a wide range of substances, facilitating various chemical reactions.
Used as a Catalyst:
4,4,5,5-TETRAMETHYL-1,3,2-DIOXAPHOSPHOLAN-2-OL, 95% also serves as a catalyst in certain chemical reactions, enhancing the rate of these processes and improving overall efficiency.
Used as an Intermediate:
4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is utilized as an intermediate in the synthesis of more complex organic compounds, playing a crucial role in multi-step chemical processes.
Used in Asymmetric Catalysis:
As a chiral ligand, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is used in asymmetric catalysis to produce enantiomerically pure compounds, which are essential in various applications, including pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4,4,5,5-Tetramethyl-1,3,2-dioxaphospholan-2-ol, 95% is used for the synthesis of biologically active molecules, contributing to the development of new drugs and therapies.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, this compound is employed for the synthesis of biologically active molecules, which can be used in the development of pesticides, herbicides, and other agricultural chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 16352-18-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,5 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16352-18:
(7*1)+(6*6)+(5*3)+(4*5)+(3*2)+(2*1)+(1*8)=94
94 % 10 = 4
So 16352-18-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H13O3P/c1-5(2)6(3,4)9-10(7)8-5/h10H,1-4H3
16352-18-4Relevant articles and documents
A two step synthesis of 2-oxo-2-vinyl 1,3,2-dioxaphospholanes and -dioxaphosphorinanes
Maffei, Michel,Buono, Gérard
, p. 8821 - 8825 (2003)
The title compounds are prepared via a two step procedure involving a transesterification between a diol and diethyl phosphite followed by a palladium-catalyzed coupling of the so-obtained cyclic phosphite with vinyl bromide. Theoretical DFT calculations have been performed on phosphonate and phosphite anions models in order to estimate stereoelectronic effects in five-membered and six-membered ring compounds.
Some properties of cyclic phosphoramidites and their phosphites: Phosphitylation, ester exchange, and hydrolysis
Watanabe, Yutaka,Maehara, Shin-Ich
, p. 799 - 810 (2007/10/03)
Phosphorylation of diols using sterically bulky cyclic phosphoramidites was performed in a good selectivity. Their phosphite derivatives underwent tetrazole-catalyzed hydrolysis and transesterification. The reaction was shown to proceed via a phosphorane intermediate by NMR analysis.
A SIMPLE AND CONVENIENT SYNTHESIS OF 2-PHOSPHONOMETHYL PYRIDINES
Page, Patrick,Mazieres, Marie-Rose,Bellan, Jacques,Sanchez, Michel
, p. 205 - 210 (2007/10/02)
The Michaelis-Becker-Nylen reaction is well suited for the synthesis of 2-phosphonomethyl pyridines.We have improved this four steps method in a one pot reaction using commercial reagents.By this general procedure we have prepared seven new 2-phosphonomethyl pyridines (Ia-g) under mild conditions with higher yields.Key words: 2-phosphono pyridines; 2-phosphonomethyl pyridines; Michaelis-Becker-Nylen reaction; new phosphonates; potential ligands.
