1643-73-8 Usage
Description
4-Fluorobenzylmagnesium chloride is an organometallic compound that serves as a crucial intermediate in various chemical reactions. It is a yellow to orange or brown solution and is known for its reactivity in organic synthesis.
Uses
Used in Organic Synthesis:
4-Fluorobenzylmagnesium chloride is used as a reagent for the synthesis of various organic compounds. Its application in this field is due to its ability to participate in a range of reactions, such as Grignard reactions, which facilitate the formation of carbon-carbon and carbon-heteroatom bonds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Fluorobenzylmagnesium chloride is used as a key intermediate for the production of various drugs. Its use in this industry is attributed to its ability to form complex molecular structures that are essential for the development of new medications.
Used in Agrochemicals:
4-Fluorobenzylmagnesium chloride is also utilized in the agrochemical industry for the synthesis of pesticides and other chemical products used in agriculture. Its application in this field is due to its role in creating compounds with specific biological activities that can help protect crops from pests and diseases.
Used in Dyestuff Industry:
In the dyestuff industry, 4-Fluorobenzylmagnesium chloride is employed as an intermediate for the production of various dyes and pigments. Its use in this industry is because of its ability to form color-producing compounds that are essential for the coloring of textiles, plastics, and other materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1643-73-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,4 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1643-73:
(6*1)+(5*6)+(4*4)+(3*3)+(2*7)+(1*3)=78
78 % 10 = 8
So 1643-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F.ClH.Mg/c1-6-2-4-7(8)5-3-6;;/h2-5H,1H2;1H;/q;;+1/p-1/rC7H6ClFMg/c8-10-5-6-1-3-7(9)4-2-6/h1-4H,5H2
1643-73-8Relevant articles and documents
Strategy for the enantioselective synthesis of trans-2,4-disubstituted piperidines: Application to the CCR3 antagonist IS811
Kauffman, Goss S.,Watson, Paul S.,Nugent, William A.
, p. 8975 - 8977 (2007/10/03)
A strategy for the enantioselective synthesis of trans-2,4-disubstituted piperidines is proposed and applied to the preparation of IS811, a potent CCR3 antagonist. The C2 stereocenter is derived from commercial (R)-epichlorohydrin, while the C4 stereocent
