16480-57-2Relevant articles and documents
Bimetallic organotin(IV) complexes with ferrocene-based azomethines: Synthesis, characterization, semi-empirical study, and antibacterial activity
Tahira, Khizra,Ali, Saqib,Shahzadi, Saira,Sharma, Saroj K.,Qanungo, Kushal
, p. 1871 - 1884 (2011)
A series of bimetallic organotin(IV) complexes with ferrocene-based azomethines (Schiff bases) were synthesized by reacting sodium salt of tranexamic acid, 4-amino butanoic acid, and phenyl alanine with trimethyltin and tributyltin chloride in 1 : 1 molar ratio under inert atmosphere. The synthesized trialkyl organotin complexes condense with formyl ferrocene under inert atmosphere to yield organotin(IV) ferrocenyl Schiff bases. Composition of the organotin(IV) complexes, bonding behavior of donor groups, and structural assignments were studied by elemental analysis, FT-IR, 1H, 13C, 119Sn NMR, and mass spectrometry. The spectral data suggest that the ligand is bidentate, coordinating through oxygens. Spectroscopic techniques reveal distorted tetrahedral geometry in solution for the complexes. As solids, the complexes are trigonal bipyramidal, confirmed by semi-empirical study. Mass spectrometric and elemental analysis data support the solid and solution spectroscopic results. Bioactivity screenings show invitro biological potential.
Natural amino acid salt catalyzed aldol reactions of isatins with ketones: highly enantioselective construction of 3-alkyl-3-hydroxyindolin-2-ones
Chen, Gong,Ju, Yuan,Yang, Tao,Li, Zicheng,Ang, Wei,Sang, Zitai,Liu, Jie,Luo, Youfu
, p. 943 - 947 (2015/09/01)
Abstract The asymmetric synthesis of 3-alkyl-3-hydroxyindolin-2-ones via direct aldol reaction of isatin with ketones catalyzed by natural amino acid salts is described, in which the phenylalanine lithium salt was found to be the best catalyst. This strategy was then applied to a variety of isatin and ketone substrates and the corresponding aldol products were obtained in excellent yields (up to 97%) with good to excellent enantioselectivities (up to 90%).
NITRIC OXIDE DONATING PROSTAMIDES
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Page/Page column 38, (2009/04/25)
Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.