165253-31-6Relevant articles and documents
Chemoselective and Tandem Reduction of Arenes Using a Metal–Organic Framework-Supported Single-Site Cobalt Catalyst
Akhtar, Naved,Begum, Wahida,Chauhan, Manav,Manna, Kuntal,Newar, Rajashree,Rawat, Manhar Singh
supporting information, (2022/01/19)
The development of heterogeneous, chemoselective, and tandem catalytic systems using abundant metals is vital for the sustainable synthesis of fine and commodity chemicals. We report a robust and recyclable single-site cobalt-hydride catalyst based on a porous aluminum metal–organic framework (DUT-5 MOF) for chemoselective hydrogenation of arenes. The DUT-5 node-supported cobalt(II) hydride (DUT-5-CoH) is a versatile solid catalyst for chemoselective hydrogenation of a range of nonpolar and polar arenes, including heteroarenes such as pyridines, quinolines, isoquinolines, indoles, and furans to afford cycloalkanes and saturated heterocycles in excellent yields. DUT-5-CoH exhibited excellent functional group tolerance and could be reusable at least five times without decreased activity. The same MOF-Co catalyst was also efficient for tandem hydrogenation–hydrodeoxygenation of aryl carbonyl compounds, including biomass-derived platform molecules such as furfural and hydroxymethylfurfural to cycloalkanes. In the case of hydrogenation of cumene, our spectroscopic, kinetic, and density functional theory (DFT) studies suggest the insertion of a trisubstituted alkene intermediate into the Co–H bond occurring in the turnover limiting step. Our work highlights the potential of MOF-supported single-site base–metal catalysts for sustainable and environment-friendly industrial production of chemicals and biofuels.
Synthesis method for 3-aminomethyl tetrahydrofuran
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Paragraph 0054; 0058; 0061; 0065-0066; 0070-0071; 0075, (2020/07/14)
The invention provides a synthetic method for 3-aminomethyl tetrahydrofuran. A target product, namely the 3-aminomethyl tetrahydrofuran is prepared by taking 2,5-dihydrofuran as an initial raw material. In the whole synthesis process, the synthesis method has the advantages of green and environmentally-friendly used raw materials, mild and conveniently-controllable reaction conditions, safe production, low risk, simple process, high yield, and more applicability to industrial production.
The invention relates to a benzofuran as raw materials for the synthesis of 3 - amino methyl tetrahydrofuran (by machine translation)
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, (2019/07/04)
The invention relates to a benzofuran as raw materials for the synthesis of 3 - amino methyl tetrahydrofuran, relates to the technical field of the synthesis intermediate for agricultural chemicals, to benzofuran as raw materials, obtained by the oxidation of the open loop 1, 4 - butene dialdehyde, and nitromethane by Michael addition, sodium borohydride reduction, dehydration cyclization and catalytic hydrogenation to five-step reaction to obtain 3 - amino methyl tetrahydrofuran. The present invention provides a benzofuran as raw materials for the synthesis of 3 - amino methyl tetrahydrofuran, the method cheap price of raw materials, synthetic route is short, low production cost, is suitable for mass production. (by machine translation)
