166411-45-6

Basic information

• Product Name: 5-O-benzoyl-2,3-dideoxy-1,2-difluoro-α-L-threo-pentofuranosyl
• Synonyms: 5-O-benzoyl-2,3-dideoxy-1,2-difluoro-α-L-threo-pentofuranosyl
• CAS NO: 166411-45-6
• Molecular Weight: 242.222
• Mol File: 166411-45-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-O-benzoyl-2,3-dideoxy-1,2-difluoro-α-L-threo-pentofuranosyl(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-benzoyl-2,3-dideoxy-1,2-difluoro-α-L-threo-pentofuranosyl(166411-45-6)
• EPA Substance Registry System: 5-O-benzoyl-2,3-dideoxy-1,2-difluoro-α-L-threo-pentofuranosyl(166411-45-6)

Safety Data

• Hazardous Substances Data: 166411-45-6(Hazardous Substances Data)

Upstream product

• 166411-42-3 1,2-O-isopropylidene-3-deoxy-3-(p-toluenesulfonylhydrazino)-5-O-benzoyl-α-L-ribofuranose 
• 166411-41-2 5-O-benzoyl-1,2-O-isopropylidene-p-toluenesulfonylhydrazone-α-L-erythro-pentofurano-3-ulose 
• 166411-43-4 5-O-benzoyl-3-deoxy-1,2-O-isopropylidene-α-L-erythro-pentofuranose 
• 166411-40-1 5-O-benzoyl-1,2-O-isopropylidene-α-L-erythro-pentofuranose-3-ulose 

Downstream Products

• 166411-46-7 5-O-benzoyl-1-bromo-2,3-dideoxy-2-fluoro-α-L-threo-pentofuranosyl 
• 255818-76-9 2-isobutyrylamino-6-chloro-9-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)purine 
• 255818-77-0 2-isobutyrylamino-6-chloro-9-(5-O-benzoyl-2,3-dideoxy-2-fluoro-α-L-threo-pentofuranosyl)purine 
• 255818-50-9 5-iodo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)uracil 
• 255818-51-0 5-iodo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-α-L-threo-pentofuranosyl)uracil 
• 255818-56-5 5-iodo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)cytosine 
• 186648-63-5 5-fluoro-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)uracil 
• 255818-47-4 5-fluoro-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-α-L-threo-pentofuranosyl)uracil 
• 255818-48-5 5-bromo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)uracil 
• 255818-49-6 5-bromo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-α-L-threo-pentofuranosyl)uracil 
• 255818-54-3 5-fluoro-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)cytosine 
• 255818-58-7 5-chloro-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)cytosine 
• 255818-55-4 5-bromo-1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)cytosine 
• 255818-59-8 1-(5-O-benzoyl-2,3-dideoxy-2-fluoro-β-L-threo-pentofuranosyl)thymine 

Relevant articles and documents

Synthesis of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides as potential antiviral agents

A series of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides has been synthesized as potential antiviral agents. The synthesized compounds were evaluated against HIV-1, HBV, HSV-1, and HSV-2. Among the synthesized analogues, only the cytosine derivative showed moderate antiviral activity against HIV and HBV.