166539-79-3

Basic information

• Product Name: 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate
• Synonyms: 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate
• CAS NO: 166539-79-3
• Molecular Weight: 356.172
• Mol File: 166539-79-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate(166539-79-3)
• EPA Substance Registry System: 2,3,4,5,6-pentafluorophenyl 4-(trifluoromethyl)benzoate(166539-79-3)

Safety Data

• Hazardous Substances Data: 166539-79-3(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 188837-53-8 (2,3,4,5,6-pentafluorophenyl)pyridine-2-carboxylate 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 
• 455-24-3 4-trifluoromethylbenzoic acid 

Downstream Products

• 728-86-9 phenyl[4-(trifluoromethyl)phenyl]methanone 
• 25771-21-5 N,N-dimethyl 4-(trifluoromethyl)benzamide 
• 447431-60-9 (pyrrolidin-1-yl)(4-(trifluoromethyl)phenyl)methanone 
• 1527472-58-7 N-ethyl-N-phenyl-4-(trifluoromethyl)benzamide 
• 724434-37-1 2-phenyl-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole 
• 771-61-9 2,3,4,5,6-pentafluorophenol 

Relevant articles and documents

Palladium-catalyzed intermolecular alkene carboacylation via ester C-O bond activation

We report palladium-catalyzed intermolecular carboacylation of alkenes with ester electrophiles and tetraarylborate nucleophiles. Bicyclic alkenes react with a variety of pentafluorophenyl benzoate and alkanoate esters and sodium tetraarylborates to form ketone products in ≤99% yields. These reactions occur in the absence of a directing group and demonstrate esters are competent acyl electrophiles for intermolecular alkene carboacylation reactions.

Aminolysis of aryl ester using tertiary amine as amino donor via c-o and c-n bond activations

An aminolysis reaction between various aryl esters and inert tertiary amines by C-O and C-N bond activations has been developed for the selective synthesis of a broad scope of tertiary amides under neutral and mild conditions. The mechanism may undergo the two key steps of oxidative addition of acyl C-O bond in parent ester and C-N bond cleavage of tertiary amine via an iminium-type intermediate.

Transesterification for synthesis of carboxylates using aldehydes as acyl donors via C-H and C-O bond activations

A new type of transesterification between aryl, heteroaryl, alkyl N-heteroarene-2-carboxylates and various aldehydes by C-H and C-O bond activations has been developed for the synthesis of versatile carboxylates. A possible mechanism containing oxidative addition of acyl-O bond in parent ester and radical cleavage of sp2 C-H bond in aldehyde is proposed.