166824-04-0

Basic information

• Product Name: Benzenemethanol, 4-methyl-a-[(1E)-2-(4-methylphenyl)ethenyl]-
• CAS NO: 166824-04-0
• Molecular Formula: C17H18O
• Molecular Weight: 238.329
• Mol File: 166824-04-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-methyl-a-[(1E)-2-(4-methylphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-methyl-a-[(1E)-2-(4-methylphenyl)ethenyl]-(166824-04-0)
• EPA Substance Registry System: Benzenemethanol, 4-methyl-a-[(1E)-2-(4-methylphenyl)ethenyl]-(166824-04-0)

Safety Data

• Hazardous Substances Data: 166824-04-0(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 122-00-9 para-methylacetophenone 
• 21551-47-3 4,4'-Dimethylchalcon 

Downstream Products

• 881397-68-8 rac-(E)-1,3-bis(4-methylphenyl)-2-propen-1-yl acetate 
• 1026688-79-8 N-[(2E)-1,3-bis(4-methylphenyl)-2-propen-1-yl]-4-methylbenzenesulfonamide 
• 1083314-30-0 C₂₄H₂₄S 
• 1379594-82-7 (E)-3-(1,3-di-p-tolylallyl)-4-hydroxy-2H-chromen-2-one 
• 1379594-86-1 (E)-4,4'-(hexa-1,5-diene-1,3-diyl)bis(methylbenzene) 
• 1092381-54-8 (E)-4,4′-(prop-1-ene-1,3-diyl)bis(methylbenzene) 
• 1352732-84-3 (E)-5-(4-methylstyryl)-1-(4-methylphenyl)-1H-tetrazole 

Relevant articles and documents

Palladium-Catalyzed Allyl-Allyl Reductive Coupling of Allylamines or Allylic Alcohols with H2as Sole Reductant

Catalytic carbon-carbon bond formation building on reductive coupling is a powerful method for the preparation of organic compounds. The identification of environmentally benign reductants is key for establishing an efficient reductive coupling reaction. Herein an efficient strategy enabling H2 as the sole reductant for the palladium-catalyzed allyl-allyl reductive coupling reaction is described. A wide range of allylamines and allylic alcohols as well as allylic ethers proceed smoothly to deliver the C-C coupling products under 1 atm of H2. Kinetic studies suggested that the dinuclear palladium species was involved in the catalytic cycle.

Preparation and Application of Amino Phosphine Ligands Bearing Spiro[indane-1,2′-pyrrolidine] Backbone

P,Nsp3-bidentate chiral ligands bearing spiro[indane-1,2′-pyrrolidine] backbone were prepared in gram scale for the first time. Pd complexes of these air-stable amino phosphine ligands could catalyze asymmetric allylic substitutions of malonate-, alcohol-, and amine-type nucleophiles in up to 97percent ee and 99percent yield. A crystal structure of [Pd(II)(η3-1,3-diphenylallyl)(ligand)]PF6 indicated possible transition states of the catalytic reactions. These ligands are characteristic of a very rigid backbone, which is simple but highly effective. They rival C2-symmetric bisphosphine, P,Nsp2-bidentate, and P,Nsp3-bidentate ligands in tested allylic substitutions. ?

Transition-Metal-Free Synthesis of Homo- and Hetero-1,2,4-Triaryl Benzenes by an Unexpected Base-Promoted Dearylative Pathway

An unprecedented approach for the synthesis of homo- and hetero-1,2,4-triaryl benzenes has been developed using a simple base-mediated reaction of either α-aryl cinnamyl alcohols or α,γ-di-aryl propanones. The salient feature of this strategy involves the sequential hydride transfer, regiospecific condensation, regiospecific dearylation, and aromatization under metal-free reaction conditions. The synthesis of unsymmetrically substituted triphenylenes by oxidative coupling of the synthesized 1,2,4-triaryl benzenes has also been demonstrated.