16728-83-9 Usage
Description
[methyl(phenyl)amino]acetonitrile, also known as Methyl(phenyl)aminoacetonitrile, is a chemical compound with the molecular formula C9H10N2. It is a colorless liquid that exhibits a faint aromatic odor. [methyl(phenyl)amino]acetonitrile is widely utilized in the fields of organic synthesis and pharmaceutical research due to its versatile nature as a building block in the synthesis of various pharmaceutical compounds. Additionally, it serves as an intermediate in the production of dyes, pigments, and other specialty chemicals.
Uses
Used in Pharmaceutical Research:
[methyl(phenyl)amino]acetonitrile is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
[methyl(phenyl)amino]acetonitrile is employed as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical products.
Used in Dye and Pigment Production:
[methyl(phenyl)amino]acetonitrile is used as an intermediate in the production of dyes and pigments, contributing to the development of new colorants for various industries.
Used in Specialty Chemicals:
[methyl(phenyl)amino]acetonitrile is also utilized in the production of specialty chemicals, where its unique properties can be harnessed for specific applications.
Safety Precautions:
Check Digit Verification of cas no
The CAS Registry Mumber 16728-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,2 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16728-83:
(7*1)+(6*6)+(5*7)+(4*2)+(3*8)+(2*8)+(1*3)=129
129 % 10 = 9
So 16728-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2/c1-8-4-2-3-5-9(8)11-7-6-10/h2-5,11H,7H2,1H3
16728-83-9Relevant articles and documents
Cyanoacetic Acid as a Masked Electrophile: Transition-Metal-Free Cyanomethylation of Amines and Carboxylic Acids
Wang, Hongxiang,Shao, Ying,Zheng, Hao,Wang, Hanghang,Cheng, Jiang,Wan, Xiaobing
supporting information, p. 18333 - 18337 (2015/12/24)
Using cyanoacetic acid as a masked electrophile, a new cyanomethylation reaction of amines and carboxylic acids was developed, producing a variety of α-aminonitriles and cyanomethyl esters with good yields and excellent functionality tolerance. This protocol features simple manipulation, inexpensive reagents, and a wide substrate scope. Iodoacetonitrile was generated in situ from the iodination-decarboxylation of cyanoacetic acid in this transformation.
