167547-59-3

Basic information

• Product Name: 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester
• Synonyms: 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester
• CAS NO: 167547-59-3
• Molecular Weight: 312.365
• Mol File: 167547-59-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester(167547-59-3)
• EPA Substance Registry System: 2-(4-methoxybenzyl)-3-oxo-3-phenylpropionic acid ethyl ester(167547-59-3)

Safety Data

• Hazardous Substances Data: 167547-59-3(Hazardous Substances Data)

Upstream product

• 54879-64-0 N-[(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 2746-25-0 p-Methoxybenzyl bromide 
• 25364-67-4 ethyl 2-benzoyl-3-(4-methoxyphenyl)acrylate 
• 696-62-8 para-iodoanisole 
• 37442-45-8 ethyl 2-(hydroxy(phenyl)methyl)propenoate 

Downstream Products

• 20566-48-7 2-[(4-methoxyphenyl)methyl]acrylic acid ethyl ester 

Relevant articles and documents

Catalytic asymmetric construction of C-4 alkenyl substituted pyrazolone derivatives bearing multiple stereoelements

An organocatalytic asymmetric process was reported for the sterically precise construction of C-4 alkenyl substituted pyrazolone derivatives bearing multiple stereoelements. A series of interesting products featuring the union of a centrally chiral pyrazolone moiety and an axially chiral styrene unit were obtained in high yield with excellent diastereoselectivity and enantioselectivity (up to 99% ee, >20?:?1 dr). The process has the characteristics of mild reaction conditions, simple operation and broad substrate scope. The result of gram-scale reaction indicates that the reaction has good practicability.

Environmentally benign nucleophilic substitution reaction of arylalkyl halides in water using CTAB as the inverse phase transfer catalyst

An environmentally benign, practically scalable and highly selective C-arylalkylation of active methylene compounds is developed using CTAB as the inverse phase transfer catalyst in water. The methodology developed is elaborated into the one-pot synthesis of quinoline derivatives and also applicable to the regioselective N-aralkyl of 2-pyridones.

Method for preparing alpha-alkyl-beta-ketone ester compound

The invention discloses a method for preparing an alpha-alkyl-beta-ketone ester compound shown as a formula (I). The method comprises the following steps: a 1,4-dihydropyridine ester compound shown asa formua (III) is taken as a reducing agent, and under existence of a Lewis acid catalyst, a compound in a formula (II) is subjected to a reduction reaction to obtain the alpha-alkyl-beta-ketone ester compound shown as the formula (I). The method has the advantages of simple operation, mild condition and environmental protection, and is suitable for a plurality of substrates, and the yield can reach as highest as 95%. By using the method of the invention, a plurality of alpha-alkyl-beta-ketone ester compounds can be efficiently prepared, types of medical intermediates are enriched, and the method has an excellent industrial application prospect.