168470-53-9

Basic information

• Product Name: 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester
• Synonyms: 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester
• CAS NO: 168470-53-9
• Molecular Weight: 465.506
• Mol File: 168470-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester(168470-53-9)
• EPA Substance Registry System: 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester(168470-53-9)

Safety Data

• Hazardous Substances Data: 168470-53-9(Hazardous Substances Data)

Upstream product

• 2279-15-4 N-(benzyloxycarbonyl)-D-tryptophan 
• 20207-16-3 ethyl 2-amino-3-oxobutanoate hydrochloride 
• 133641-28-8 C₂₄H₂₆N₂O₆ 

Downstream Products

• 168470-76-6 2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-2-(1H-indol-3-yl)-ethyl]-5-methyl-thiazole-4-carboxylic acid ethyl ester 
• 168470-79-9 2-[(R)-1-Benzyloxycarbonylamino-2-(1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid ethyl ester 
• 168470-54-0 2-[(R)-1-Benzyloxycarbonylamino-2-(1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid ethyl ester 
• 168470-73-3 2-[(R)-1-Benzyloxycarbonylamino-2-(1H-indol-3-yl)-ethyl]-5-methyl-thiazole-4-carboxylic acid ethyl ester 

Relevant articles and documents

Azole endothelin antagonists. 1. A receptor model explains an unusual structure-activity profile

The pseudotetrapeptide FR-139317 is a potent and highly selective antagonist of the endothelin-A (ET(A)) receptor; however, its peptidic nature leads to poor oral absorption characteristics which make it an unlikely drug candidate. In an attempt to improv