20207-16-3

Basic information

• Product Name: ethyl 2-amino-3-oxobutanoate hydrochloride
• Synonyms: ethyl 2-amino-3-oxobutanoate hydrochloride;2-Amino-3-oxobutanoic acid ethyl ester hydrochloride;Ethyl 2-aminoacetoacetate hydrochloride;Ethyl alpha-aminoacetoacetate hydrochloride;Butanoic acid, 2-aMino-3-oxo-, ethyl ester, hydrochloride;Ethyl 2-amino-3-oxobutanoate, HCl
• CAS NO: 20207-16-3
• Molecular Formula: C₆H₁₁NO₃*ClH
• Molecular Weight: 182
• Mol File: 20207-16-3.mol
• Article Data: 12

Chemical Properties

• Melting Point: 114-115℃
• Boiling Point: 229.2 °C at 760 mmHg
• Flash Point: 92.4 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: ethyl 2-amino-3-oxobutanoate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-3-oxobutanoate hydrochloride(20207-16-3)
• EPA Substance Registry System: ethyl 2-amino-3-oxobutanoate hydrochloride(20207-16-3)

Safety Data

• Hazardous Substances Data: 20207-16-3(Hazardous Substances Data)

Usage

Uses

Ethyl 2-amino-3-oxobutanoate, HCl

Upstream product

• 5408-04-8 ethyl 2-hydroxyimino-3-oxobutanoate 
• 51026-98-3 ethyl 2-nitro-3-oxobutyrate 
• 141-97-9 ethyl acetoacetate 
• 178200-66-3 (2RS)-tert-butoxycarbonylamino-3-oxo-butyric acid ethyl ester 
• 66508-94-9 2-[(E)-hydroxyimino]-3-oxobutyric acid ethyl ester 

Downstream Products

• 3284-51-3 ethyl 5-methyl-1H-pyrrole-2-carboxylate 
• 29170-87-4 diethyl 3-methyl-pyrrole-2,5-dicarboxylate 
• 21898-53-3 <2,4-Dimethyl-5-ethoxycarbonyl-pyrryl-(3)>-glyoxylsaeureester 
• 5463-44-5 ethyl 3,5-dimethyl-4-nitropyrrole-2-carboxylate 
• 107367-59-9 2-[(E)-3-(4-Methoxy-phenyl)-acryloylamino]-3-oxo-butyric acid ethyl ester 
• 107367-56-6 2-[(E)-3-(3-Chloro-phenyl)-acryloylamino]-3-oxo-butyric acid ethyl ester 
• 107367-55-5 2-[(E)-3-(4-Chloro-phenyl)-acryloylamino]-3-oxo-butyric acid ethyl ester 
• 2436-79-5 diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 
• 61151-90-4 2-benzoylamino-3-oxobutyric acid ethyl ester 
• 89723-84-2 ethyl 2-cinnamoylaminoacetoacetate 
• 61151-95-9 2-cyclohexanecarbonylamino-3-oxo-butyric acid ethyl ester 
• 107367-57-7 2-[(E)-3-(2-Chloro-phenyl)-acryloylamino]-3-oxo-butyric acid ethyl ester 
• 168470-53-9 2-[(R)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-oxo-butyric acid ethyl ester 
• 123-32-0 2,5-dimethyl-pyrazine 

Relevant articles and documents

OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE

The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in inter alia the treatment of cancer is disclosed. Formula (I)

OXAZOLE OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to oxazole compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the oxazole compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.