168827-86-9

Basic information

• Product Name: Carbamic acid, [(2S)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(2S)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 168827-86-9
• Molecular Formula: C₉H₁₉NO₃
• Molecular Weight: 189.25206
• Product Categories: N-BOC
• Mol File: 168827-86-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, [(2S)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2S)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(168827-86-9)
• EPA Substance Registry System: Carbamic acid, [(2S)-3-hydroxy-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(168827-86-9)

Safety Data

• Hazardous Substances Data: 168827-86-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1429320-33-1 ethyl (S)-3-(tert-butoxycarbonylamino)-2-methylpropanoate 
• 1312771-12-2 ethyl 2-[(bis(tert-butoxycarbonyl)amino)methyl]acrylate 
• 51779-32-9 iminodicarboxylic acid di-tert-butyl ester 
• 374729-55-2 (S)-tert-butyl (2-methyl-3-oxopropyl)carbamate 
• 168828-18-0 methyl (S)-3-(tert-butoxycarbonylamino)-2-methylpropanoate 

Downstream Products

• 374729-51-8 tert-Butyl N-[(2R,3E)-2-methyl-3-hexen-5-ynyl]carbamate 
• 374729-55-2 (S)-tert-butyl (2-methyl-3-oxopropyl)carbamate 

Relevant articles and documents

CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE

The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Rhodium-catalyzed asymmetric hydroformylation of n-allvlamides: Highly enantioselective approach to β2-amino aldehydes

(Figure Presented) You're having a lahf I The asymmetric hydroformylation (AHF) of allylic compounds, catalyzed by a rhodium-yanphos complex, is a direct and concise route to ss2-amino aldehydes, acids, and alcohols with excellent enantioselectivity (see scheme; TON =turnover number, acac = acetylacetonate).

ANTITHROMBOTIC ETHERS

This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor (I).