168828-18-0Relevant articles and documents
Synthesis of enantiopure β2-homoalanine derivatives via rhodium catalyzed asymmetric hydrogenation
Luehr, Susan,Holz, Jens,Zayas, Odalys,Seidelmann, Oliver,Domke, Lutz,Boerner, Armin
, p. 395 - 401 (2013/06/27)
The stereoselective synthesis of chiral β2-homoalanine derivatives with 99% ee by the Rh-catalyzed enantioselective hydrogenation of prochiral 2-aminomethyl acrylates is described. The subsequent transformation to chiral 3-amino-2-methylpropanols is also demonstrated.