169894-59-1

Basic information

• Product Name: 3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one
• Synonyms: 3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one
• CAS NO: 169894-59-1
• Molecular Weight: 246.309
• Mol File: 169894-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one(169894-59-1)
• EPA Substance Registry System: 3-(4-phenylpiperazin-1-yl)-tetrahydrofuran-2-one(169894-59-1)

Safety Data

• Hazardous Substances Data: 169894-59-1(Hazardous Substances Data)

Upstream product

• 5061-21-2 α-bromo-γ-butyrolactone 
• 92-54-6 4-phenyl-1-piperazine 

Downstream Products

• 172883-63-5 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-fluorobenzylamide) 
• 172883-62-4 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-(4-methoxybenzylamide) 
• 172883-59-9 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid N-benzylamide 
• 193752-72-6 α-(4-phenylpiperazine)-γ-hydroxybutyric acid, N-benzylamide 
• 172883-57-7 2-(4-Phenylpiperazine)-4-phthalimidobutyric acid 
• 169894-63-7 α-(4-phenylpiperazino)-γ-hydroxybutyric acid N-(4-fluorobenzylamide) 

Relevant articles and documents

Synthesis, physicochemical and pharmacological properties of new N-substituted amides of α-piperazine-γ-hydroxybutyric acid

Synthesis and physicochemical properties of new N-substituted amides of α-piperazine-γ-hydroxybutyric acid are described. The compounds were obtained by aminolysis of 3-(4-phenyl) or 4-benzyl)-piperazine-tetrahydrofuran-2-on with primary alkylarylamines. Preliminary pharmacological assessment revealed the activity in two sensorimotor tests for of the novel compounds: N-(4-fluoro) and N-(4-chlorobenzylamide) of α-(4-phenylpiperazine)-γ-hydroxybutyric acid.