171357-23-6

Basic information

• Product Name: (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE
• Synonyms: (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE;(R,R)-1,2-Diamino-1,2-di-tert-butylethane
• CAS NO: 171357-23-6
• Molecular Formula: C₁₀H₂₄N₂
• Molecular Weight: 172.31096
• Mol File: 171357-23-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE(171357-23-6)
• EPA Substance Registry System: (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE(171357-23-6)

Safety Data

• Hazardous Substances Data: 171357-23-6(Hazardous Substances Data)

Usage

Description

(R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is an organic compound that belongs to the class of amines. It is a symmetric diamine with four methyl groups attached to the carbon atoms, making it a unique and versatile building block in organic chemistry. (R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is commonly used as a chiral ligand in asymmetric synthesis and catalysis, which is crucial for the production of pharmaceuticals and fine chemicals with specific stereochemistry.

Uses

Used in Pharmaceutical Industry:
(R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is used as a chiral ligand for [application reason] the synthesis of complex molecules with specific stereochemistry. Its unique structure allows for the creation of pharmaceuticals with desired properties and improved efficacy.
Used in Fine Chemicals Industry:
(R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is used as a chiral ligand for [application reason] the production of fine chemicals with precise stereochemistry. This is essential for the development of high-quality chemicals with specific applications in various industries, such as fragrances, dyes, and agrochemicals.
Used in Asymmetric Synthesis:
(R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is used as a chiral ligand for [application reason] facilitating asymmetric synthesis reactions. This enables the creation of enantiomerically pure compounds, which are essential in various fields, including pharmaceuticals, agrochemicals, and materials science.
Used in Catalysis:
(R,R)-3,4-DIAMINO-2,2,5,5-TETRAMETHYLHEXANE is used as a chiral ligand for [application reason] enhancing the selectivity and efficiency of catalytic reactions. This is particularly important in the production of optically active compounds, which have significant applications in the pharmaceutical and chemical industries.

Upstream product

• 221638-36-4 N,N'-bis<(S)-1-phenylethyl>-(R,R)-1,2-diamino-1,2-di-tert-butylethane 

Downstream Products

• 1224151-64-7 (1R,2R)-1-amino-2-(2-isopropyl-4-methoxy-5-tert-butylbenzenamine)-1,2-di-tertbutylethane 
• 942513-37-3 (1R,2R)-1-amino-2-(2-isopropylbenzenamine)-1,2-di-tert-butylethane 
• 1301707-87-8 (4R,5R)-4,5-di-tert-butyl-2-(2'-fluorophenyl)-4,5-dihydro-1H-imidazole 
• 1268872-77-0 C₂₈H₄₉IN₄ 
• 1083366-17-9 (R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-2,2,5,5-tetramethylhexane-3,4-diamine 
• 866044-18-0 (1R,2R)-1,2-N,N'-bis(p-toluenesulfonylamino)-1,2-di-tert-butylethane 

Relevant articles and documents

A New, Short, and Stereocontrolled Synthesis of C2-Symmetric 1,2-Diamines

The previously unknown 5-spirocyclohexylisoimidazole has been made efficiently and simply by reaction of ammonia, glyoxal hydrate, and cyclohexanone. It is a very useful precursor for the diastereocontrolled synthesis of many C2-symmetric 1,2-diamines, a class which is important for the generation of a variety of C2-symmetric reagents and catalysts for enantioselective synthesis.

Titanium(IV)(salen) and yanadium(V)(salen) complexes derived from C 2- and C1-symmetric diamines for asymmetric cyanohydrin synthesis

Titanium and vanadium salen complexes have been prepared from C 2- and C1-symmetric acyclic diamines. All of the complexes catalysed the asymmetric addition of trimethylsilyl cyanide to benzaldehyde and the sense of asymmetric induction was determined by the nature of the substituents. The vanadium complex of a valine-derived diamine gave good results with a range of aromatic and aliphatic aldehydes. Georg Thieme Verlag Stuttgart.

Chiral bis(N-sulfonylamino)phosphine- and TADDOL-phosphite-oxazoline ligands: Synthesis and application in asymmetric catalysis

A series of N,P-ligands has been prepared, containing a chiral oxazoline ring and as a second chiral unit a bis(N-sulfonylamino)phosphine group embedded in a diazaphospholidine ring or a cyclic phosphite group derived from TADDOL. These modular ligands are readily synthesized from chiral amino alcohols and chiral 1,2-diamines or TADDOLs. Palladium and iridium complexes derived from these ligands were found to be efficient catalysts for enantioselective allylic alkylation and olefin hydrogenation, respectively.