221638-36-4

Basic information

• Product Name: 3,4-Hexanediamine, 2,2,5,5-tetramethyl-N,N'-bis[(1S)-1-phenylethyl]-, (3R,4R)-
• CAS NO: 221638-36-4
• Molecular Formula: C26H40N2
• Molecular Weight: 380.617
• Mol File: 221638-36-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3,4-Hexanediamine, 2,2,5,5-tetramethyl-N,N'-bis[(1S)-1-phenylethyl]-, (3R,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Hexanediamine, 2,2,5,5-tetramethyl-N,N'-bis[(1S)-1-phenylethyl]-, (3R,4R)-(221638-36-4)
• EPA Substance Registry System: 3,4-Hexanediamine, 2,2,5,5-tetramethyl-N,N'-bis[(1S)-1-phenylethyl]-, (3R,4R)-(221638-36-4)

Safety Data

• Hazardous Substances Data: 221638-36-4(Hazardous Substances Data)

Upstream product

• 594-19-4 tert.-butyl lithium 
• 509148-39-4 4(R),5(R)-di[1(S)-phenylethylamino]-3(R),6(R)-diphenyl-1,7-octadiene 
• 677-22-5 tert-butylmagnesium chloride 
• 129171-89-7 1,4-bis<(R)-α-methylbenzyl>-1,4-diaza-1,3-butadiene 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 138812-17-6 N,N'-bis<(S)-1-phenylethyl>ethanediimine 

Downstream Products

• 221638-37-5 (1R,2R)-N,N'-bis<(S)-1-phenylethyl>-1,2-di-tert-butylimidazolidine 
• 171357-23-6 (3R,4R)-3,4-diamino-2,2,5,5-tetramethylhexane 
• 866044-18-0 (1R,2R)-1,2-N,N'-bis(p-toluenesulfonylamino)-1,2-di-tert-butylethane 

Relevant articles and documents

Improved chiral olefin metathesis catalysts: Increasing the thermal and solution stability via modification of a C1-symmetrical N-heterocyclic carbene ligand

Four new ruthenium-based olefin metathesis catalysts that possess an N-heterocyclic carbene (NHC) ligand with benzyl (Bn) or or n-propyl (n-Pr) N-alkyl groups have been prepared. The synthetic routes developed for the synthesis of the required dihydroimid

Chiral bis(N-sulfonylamino)phosphine- and TADDOL-phosphite-oxazoline ligands: Synthesis and application in asymmetric catalysis

A series of N,P-ligands has been prepared, containing a chiral oxazoline ring and as a second chiral unit a bis(N-sulfonylamino)phosphine group embedded in a diazaphospholidine ring or a cyclic phosphite group derived from TADDOL. These modular ligands are readily synthesized from chiral amino alcohols and chiral 1,2-diamines or TADDOLs. Palladium and iridium complexes derived from these ligands were found to be efficient catalysts for enantioselective allylic alkylation and olefin hydrogenation, respectively.

Synthesis of chiral C2-symmetric 1,2-diamines by the addition of organolithium reagents to N,N'-bis[(S)-1-phenylethyl]ethanediimine

The additions of alkyl-, phenyl- and vinyllithium reagents to N,N'-bis[(S)-1-phenylethyl]ethanediimine in THF at -78°C and in DME at -60°C gave high yields of 1,2-diamines with low stereocontrol. Care was taken to quench the reaction mixtures with de-aera