171416-77-6

Basic information

• Product Name: 1,7-dicarboxymethyl-4,10-di(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane
• Synonyms: 1,7-dicarboxymethyl-4,10-di(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane
• CAS NO: 171416-77-6
• Molecular Weight: 596.726
• Mol File: 171416-77-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,7-dicarboxymethyl-4,10-di(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-dicarboxymethyl-4,10-di(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane(171416-77-6)
• EPA Substance Registry System: 1,7-dicarboxymethyl-4,10-di(p-toluenesulfonyl)-1,4,7,10-tetraazacyclododecane(171416-77-6)

Safety Data

• Hazardous Substances Data: 171416-77-6(Hazardous Substances Data)

Upstream product

• 134448-29-6 1,7-bis(4-toluenesulphonyl)-1,4,7,10-tetraazacyclododecane 
• 79-08-3 bromoacetic acid 
• 52667-88-6 cyclen tetratosylate 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Synthesis of dicarboxymethyl tetraazacyclododecane derivatives for polycondensation

Three different routes to synthesize selectively protected tetraaza macrocycles bifunctionalized with carboxymethyl acid groups have been developed in order to obtain monomers for polycondensation. The first way has been carried out from cyclen, whose synthesis has been improved, requires 6 steps. The second way allowed to obtain the bifunctional protected macrocycle from ethylenediamine and diethyl iminodiacetate in 2 steps. The last way has consisted in synthesizing directly a monomer by cyclization from ethylenediaminetetraacetic acid bisanhydride and ethylenediamine.