171623-29-3Relevant articles and documents
COMPOUNDS AND METHOD OF USE
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, (2019/09/06)
This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.
CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS
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, (2014/09/29)
Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.
Properties of the Liquid Crystals Formed by Ceratin Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes
Brown, J. W.,Byron, D. J.,Southcott, M.,Wilson, R. C.,Guillon, D.,et al.
, p. 37 - 52 (2007/10/02)
The liquid crystal behaviour of four homologous series of azomethines related to the nO.m series but containing a cycloalkyl group, is reported and discussed.Many of these compounds show extensive smectic polymorphism, one member of the nO.c6 series giving rise to five smectic polymorphic modofications for which phase type assignments have been made by thermal optical microscopy.Keywords: smectic polymorphism, azomethines, cycloalkyl derivatives