1722-69-6

Basic information

• Product Name: (3Z)-3,4-diphenylbut-3-en-2-one
• CAS NO: 1722-69-6
• Molecular Formula: C₁₆H₁₄O
• Molecular Weight: 222.2818
• Mol File: 1722-69-6.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 367.3°C at 760 mmHg
• Flash Point: 139.6°C
• Density: 1.078g/cm³
• Vapor Pressure: 1.38E-05mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: (3Z)-3,4-diphenylbut-3-en-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3Z)-3,4-diphenylbut-3-en-2-one(1722-69-6)
• EPA Substance Registry System: (3Z)-3,4-diphenylbut-3-en-2-one(1722-69-6)

Safety Data

• Hazardous Substances Data: 1722-69-6(Hazardous Substances Data)

Usage

General Description

(3Z)-3,4-diphenylbut-3-en-2-one, also known as chalcone, is a compound with the chemical formula C16H12O. It is a yellow solid that is commonly found in plants and fruits. Chalcone is known for its anti-inflammatory, antioxidant, and anti-cancer properties, and it has been studied for its potential therapeutic applications. Its structure consists of a chalcone skeleton, which is a key intermediate in the biosynthesis of flavonoids. Chalcone is also used as a starting material in the synthesis of various pharmaceuticals and other organic compounds. Due to its versatile nature and potential biological activities, chalcone continues to be an important compound in the fields of medicine, agriculture, and material science.

Upstream product

• 7647-01-0 hydrogenchloride 
• 327077-79-2 4-chloro-3,4-diphenyl-butan-2-one 
• 123-39-7 N-Methylformamide 
• 103-79-7 1-phenyl-acetone 
• 593-51-1 methylamine hydrochloride 
• 100-52-7 benzaldehyde 
• 15341-31-8 α-nitro-stilbene 
• 1483-72-3 diphenyliodonium chloride 
• 1247-08-1 Triphenyl-phenylethynyl-stannane 
• 75-36-5 acetyl chloride 
• 501-65-5 diphenyl acetylene 
• 17203-28-0 3-diazo-4-phenyl-2-butanone 
• 98-80-6 phenylboronic acid 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 27363-82-2 α-Acetoxymethylencarbonyl-stilben 
• 70974-73-1 1-nitro-1,2-diphenyl-1-butene-3-one 
• 67-66-3 chloroform 
• 91-48-5 (E)-2,3-diphenylpropenoic acid 
• 94897-34-4 3,4-diphenyl-2-butanone 
• 120638-24-6 3-methyl-1,4,5-triphenyl-1H-pyrazole 
• 75115-00-3 3-methyl-4,5-diphenylisoxazole 
• 80459-94-5 trans-2-methyl-3,4,5-triphenylcyclopent-2-en-1-one 
• 1056-77-5 2,3,4,5-tetraphenylfuran 

Relevant articles and documents

A stereoselective synthetic route to (Z)-α-organostannyl-α,β-unsaturated carbonyl compounds

Hydrozirconation of acetylenic stannanes 1 affords gemstannazirconocene alkenes 2. Intermediates 2 are treated with acyl halides to obtain (Z)-α-organostannyl-α,β-unsaturated carbonyl compounds 3 via Zr-Cu transmetallation.

Stereospecific Decarboxylative Nazarov Cyclization Mediated by Carbon Dioxide for the Preparation of Highly Substituted 2-Cyclopentenones

Highly substituted 2-cyclopentenones were stereospecifically and regioselectively constructed with high catalytic efficiency through Lewis-acid catalyzed decarboxylative Nazarov cyclization of the cyclic carbonate derivative, which is prepared by reacting the propargyl alcohol with carbon dioxide in the presence of a silver catalyst. The stereochemistry of the 2-cyclopentenone is strictly controlled by the geometry of the alkene in the starting material. This method is applicable for various substrates.

Acid-catalyzed synthesis of α,β-disubstituted conjugated enones by a Meyer-Schuster-type rearrangement in allenols

A novel, direct and simple methodology to gain access to α,β-disubstituted conjugated enones from α-allenols in a sustainable metal catalysis context, considering the inexpensiveness and environmentally friendliness of iron(III) species and protons, has b