172656-35-8Relevant articles and documents
[3,3]-Rearrangements of phosphonium ylides
Ferguson, Marcelle L.,Senecal, Todd D.,Groendyke, Todd M.,Mapp, Anna K.
, p. 4576 - 4577 (2006)
Allylic phosphonium ylides are readily generated by the combination of an allylic alcohol, a carbene, and a chlorophosphite. Here we demonstrate that these intermediates undergo a thermal [3,3]-rearrangement to provide single isomers of homoallylic phosph
Stereoselective synthesis of functionalized 1,4-dienes
Khamri, Sonia,Turki, Taoufik,Amri, Hassen
, p. 3277 - 3284 (2008/12/23)
The article reports a stereoselective synthesis of functionalized 1,4-dienes 5, 6 by coupling allylic Baylis-Hillman acetates 1 and vinyl magnesium chloride at low temperature and in the presence of a catalytic amount of LiCuBr2 (3%). Copyright Taylor & Francis Group, LLC.
Efficient synthesis of α-benzylidene-γ-methyl-γ-butyrolactones
Mali, Raghao S.,Babu, Kantipudi N.
, p. 3525 - 3531 (2007/10/03)
A concise synthesis of α-benzylidene-γ-methyl-γ-butyrolactones 5a - g from substituted benzaldehydes is described. Compounds 1a - g on reaction with phosphorane 2, provide the pentenoates 3a - g, which can be hydrolyzed to the acids 4a - g. The latter are cyclized to the corresponding butyrolactones 5a - g in excellent yields. The pentenoates 3a - g, on acid catalyzed cyclization, also provide 5a - g in very high yields.
