172877-72-4Relevant articles and documents
A Formal Approach to Xylosmin and Flacourtosides E and F: Chemoenzymatic Total Synthesis of the Hydroxylated Cyclohexenone Carboxylic Acid Moiety of Xylosmin
Ghavre, Mukund,Froese, Jordan,Murphy, Brennan,Simionescu, Razvan,Hudlicky, Tomas
, p. 1156 - 1159 (2017)
The hydroxylated cyclohexenone carboxylic acid moiety of xylosmin was synthesized in eight steps from benzoic acid. The key steps in the synthesis involved the enzymatic dihydroxylation of benzoic acid by the whole cell fermentation with Ralstonia eutroph
A Chemoenzymatic Formal Synthesis of Epoxyquinols A and B
Collins, Jonathan A.,Duncan, Madeleine M.,Gerry, Christopher J.
, p. 2193 - 2197 (2019/11/25)
A formal synthesis of epoxyquinols A and B was completed in nine steps starting from benzoic acid. Enantioselectivity was established through an enzymatic arene dihydroxylation reaction performed by whole cells of Ralstonia eutropha B9 expressing benzoate
Synthesis of a broad array of highly functionalized, enantiomerically pure cyclohexanecarboxylic acid derivatives by microbial dihydroxylation of benzoic acid and subsequent oxidative and rearrangement reactions
Myers, Andrew G.,Siegel, Dionicio R.,Buzard, Daniel J.,Charest, Mark G.
, p. 2923 - 2926 (2007/10/03)
(equation presented) We have found that the 1,2-dihydroxylation of benzoic acid with Alcaligenes eutrophus strain B9, first reported in 1971 by Reiner and Hegeman, is readily adapted for the preparation of tens to hundreds of grams of (1S,2R)-1,2-dihydrox