17327-22-9 Usage
Description
5,6-Dihydro-4-methoxy-2H-pyran is a suitable reagent for the protection of nucleoside hydroxyl functions and has been utilized in the solid-phase synthesis of a series of oligoribonucleotides. It is a valuable compound in the field of organic chemistry, particularly for the synthesis and protection of chiral alcohols.
Uses
Used in Pharmaceutical Industry:
5,6-Dihydro-4-methoxy-2H-pyran is used as a reagent for the protection of chiral alcohols, which is crucial in the synthesis of various pharmaceutical compounds. Its ability to protect nucleoside hydroxyl functions allows for the selective synthesis of complex molecules with specific biological activities.
Used in Chemical Research:
In the field of chemical research, 5,6-Dihydro-4-methoxy-2H-pyran is used as a reagent for the solid-phase synthesis of oligoribonucleotides. This application is significant for the development of new drugs and the study of molecular biology, as oligoribonucleotides can be used as therapeutic agents and research tools.
Used in Synthesis of Oligoribonucleotides:
5,6-Dihydro-4-methoxy-2H-pyran is used as a key reagent in the solid-phase synthesis of a series of oligoribonucleotides. This process is essential for the development of new drugs and the study of genetic information, as oligoribonucleotides can be used to manipulate gene expression and understand the function of specific genes.
Overall, 5,6-Dihydro-4-methoxy-2H-pyran is a versatile compound with applications in various industries, including pharmaceuticals, chemical research, and the synthesis of oligoribonucleotides. Its ability to protect chiral alcohols and nucleoside hydroxyl functions makes it a valuable tool in the development of new drugs and the advancement of scientific knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 17327-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,2 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17327-22:
(7*1)+(6*7)+(5*3)+(4*2)+(3*7)+(2*2)+(1*2)=99
99 % 10 = 9
So 17327-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O2/c1-7-6-2-4-8-5-3-6/h2H,3-5H2,1H3
17327-22-9Relevant articles and documents
SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Paragraph 0386, (2016/05/02)
Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.
Efficient preparation of 4-methoxy-5,6-dihydro-2H-pyran
Panchal, Nitesh,Fernandez-Yarza, Arantxa,Free, Paul,Gaffney, Piers R.J.
, p. 1836 - 1838 (2008/09/18)
We report the efficient synthesis of 4-methoxy-5,6-dihydro-2H-pyran (MDHP) via the TiCl4 driven elimination of MeOH from 4,4-dimethoxytetrahydropyran. The previous difficulty of preparing MDHP restricted the wider use of 4-methoxytetrahydropyran-4-yl (MTHP) acyclic acetals, which have desirable protecting group properties when compared to more commonly used MOM- and THP-acetals. The behaviour of the elimination on related acetals is also examined.