1738-69-8

Basic information

• Product Name: benzyl L-leucinate
• Synonyms: benzyl L-leucinate;Leucine benzyl;L-Leucine benzyl ester;Einecs 217-093-0;L-Leucine, phenylMethyl ester
• CAS NO: 1738-69-8
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.29546
• EINECS: 217-093-0
• Mol File: 1738-69-8.mol
• Article Data: 27

Chemical Properties

• Melting Point: 135-145 °C
• Boiling Point: 302.5°Cat760mmHg
• Flash Point: 157.6°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 0.000987mmHg at 25°C
• Refractive Index: 1.515
• PKA: 7.85±0.42(Predicted)
• CAS DataBase Reference: benzyl L-leucinate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl L-leucinate(1738-69-8)
• EPA Substance Registry System: benzyl L-leucinate(1738-69-8)

Safety Data

• Hazardous Substances Data: 1738-69-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H19NO2/c1-10(2)8-12(14)13(15)16-9-11-6-4-3-5-7-11/h3-7,10,12H,8-9,14H2,1-2H3/t12-/m0/s1

Upstream product

• 61-90-5 L-leucine 
• 98-11-3 benzenesulfonic acid 
• 100-51-6 benzyl alcohol 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 100-44-7 benzyl chloride 
• 15761-38-3 L-N-Boc-Ala 
• 82333-01-5 L-leucine benzyl ester p-toluenesulfonate 
• 87746-56-3 2-tert-butoxycarbonylamino-4-methyl-penatnoic acid benzyl ester 
• 2462-35-3 L-leucine benzyl ester hydrochloride 
• 2666-93-5 (S)-Leu-OMe 
• 80089-22-1 L-leucine (phenylmethyl)ester 
• 100-39-0 benzyl bromide 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 

Downstream Products

• 73994-87-3 (S)-benzyl 2-((S)-2-amino-3-phenylpropanamido)-4-methylpentanoate hydrochloride 
• 38689-31-5 _(D)Leu-_(L)Leu 
• 103321-61-5 Fmoc-Phe-Leu-OBzl 
• 75657-73-7 N-((2S,3S)-3-trans-ethoxycarbonyloxiran-2-carbonyl)-L-leucine benzyl ester 
• 175793-29-0 (S)-2-[(2S,3R)-2-Benzylamino-3-(tert-butyl-diphenyl-silanyloxy)-4-methyl-pentanoylamino]-4-methyl-pentanoic acid benzyl ester 
• 197453-30-8 (S)-2-((S)-1,4-Dioxo-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl)-4-methyl-pentanoic acid benzyl ester 
• 141595-75-7 (S)-2-[(azepane-1-carbonyl)-amino]-4-methyl-pentanoic acid benzyl ester 
• 246506-78-5 2-(3-tert-butoxycarbonylamino-2-oxo-4-phenylbutyrylamino)-4-methylpentanoic acid benzyl ester 
• 190007-81-9 (S)-2-[(S)-2-Benzylamino-2-((4S,5S)-5-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetylamino]-4-methyl-pentanoic acid benzyl ester 
• 182205-65-8 (S)-2-{(S)-2-[((2S,3R)-2-Amino-3-methyl-pentanoyl)-methyl-amino]-3-methyl-butyrylamino}-4-methyl-pentanoic acid benzyl ester 
• 175777-26-1 (S)-2-[((3S,6S,8aR)-3-{2-[(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-4-oxo-hexahydro-pyrrolo[2,1-b][1,3]oxazine-6-carbonyl)-amino]-4-methyl-pentanoic acid benzyl ester 
• 175659-67-3 (S)-2-[((3S,6S,8aS)-3-{2-[(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-4-oxo-hexahydro-pyrrolo[2,1-b][1,3]oxazine-6-carbonyl)-amino]-4-methyl-pentanoic acid benzyl ester 
• 175659-66-2 (S)-2-[((3S,6S,8aS)-3-Amino-4-oxo-hexahydro-pyrrolo[2,1-b][1,3]oxazine-6-carbonyl)-amino]-4-methyl-pentanoic acid benzyl ester 
• 175777-25-0 (S)-2-{[(3S,6S,8aR)-3-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-oxo-hexahydro-pyrrolo[2,1-b][1,3]oxazine-6-carbonyl]-amino}-4-methyl-pentanoic acid benzyl ester 

Relevant articles and documents

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Metal-free transesterification catalyzed by tetramethylammonium methyl carbonate

Environmentally benign metal-free tetramethylammonium methyl carbonate is effective as a catalyst for the chemoselective, scalable, and reusable transesterification of various esters and alcohols in common organic solvents. In situ-generated highly active species, tetramethylammonium alkoxides, can greatly avoid self-decomposition at ≤110 °C, and are reusable. In particular, chelating substrates, such as amino alcohols, diols, triols, sugar derivatives, alkaloids, α-amino acid esters, etc., which deactivate conventional metal salt catalysts, can be used. A 100 gram scale biodiesel production was also demonstrated.

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