17386-89-9 Usage
Description
1-(3,4-Dihydroxyphenyl)butan-1-one, also known as 3',4'-Dihydroxy-1-phenyl-2-butanone (CAS# 17386-89-9), is an organic compound with a grey solid appearance. It is characterized by the presence of a butanone group attached to a phenyl ring, which features two hydroxyl groups at the 3' and 4' positions. This unique structure endows it with specific chemical properties that make it valuable in various applications.
Uses
Used in Organic Synthesis:
1-(3,4-Dihydroxyphenyl)butan-1-one is used as an intermediate in the synthesis of various organic compounds. Its chemical structure allows for further functionalization and modification, making it a versatile building block for the creation of more complex molecules with diverse applications in the chemical, pharmaceutical, and materials science industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(3,4-Dihydroxyphenyl)butan-1-one is used as a key component in the development of new drugs. Its unique structure can be exploited to design and synthesize novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Materials Science:
1-(3,4-Dihydroxyphenyl)butan-1-one can also be utilized in the field of materials science for the development of new materials with specific properties. Its chemical structure can be tailored to create materials with enhanced performance characteristics, such as improved mechanical strength, thermal stability, or electrical conductivity.
Used in Chemical Research:
As a compound with distinct chemical properties, 1-(3,4-Dihydroxyphenyl)butan-1-one is used in chemical research to study various reaction mechanisms, explore new synthetic routes, and develop innovative methodologies in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 17386-89-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,8 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 17386-89:
(7*1)+(6*7)+(5*3)+(4*8)+(3*6)+(2*8)+(1*9)=139
139 % 10 = 9
So 17386-89-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-2-3-8(11)7-4-5-9(12)10(13)6-7/h4-6,12-13H,2-3H2,1H3
17386-89-9Relevant articles and documents
A convenient synthetic approach to dioncoquinone B and related compounds
Khmelevskaya, Ekaterina A.,Pelageev, Dmitry N.
supporting information, p. 1022 - 1024 (2019/03/13)
A total synthesis of dioncoquinone B and related compounds, including ancistroquinones B, C and malvon A, is presented. The strategy is based on available reagents and can be used as a preparative synthesis of a number of natural and synthetic biologically active (3-alkyl)-2,7,8-di(tri)methoxy(hydroxy)-1,4-naphthoquinones.
The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors
Xiao, Zhu-Ping,Ma, Tao-Wu,Fu, Wei-Chang,Peng, Xiao-Chun,Zhang, Ai-Hua,Zhu, Hai-Liang
experimental part, p. 5064 - 5070 (2010/12/24)
Some pyrogallol and catechol derivatives were synthesized, and their urease inhibitory activity was evaluated by using acetohydroxamic acid (AHA), a well known Helicobacter pylori urease inhibitor, as positive control. The assay results indicate that many compounds have showed potential inhibitory activity against H. pylori urease. 4-(4-Hydroxyphenethyl)phen-1,2-diol (2a) was found to be the most potent urease inhibitor with IC50s of 1.5 ± 0.2 μM for extracted fraction and 4.2 ± 0.3 μM for intact cell, at least 10 times and 20 times lower than those of AHA (IC50 of 17.2 ± 0.9 μM, 100.6 ± 13 μM), respectively. This finding indicate that 2a would be a potential urease inhibitor deserves further research. Molecular dockings of 2a into H. pylori urease active site were performed for understanding the good activity observed.
