173989-76-9 Usage
Description
(R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid, a pyrrole carboxylic acid derivative, is a chiral compound characterized by a chiral center at the carbon atom bonded to the phenylethyl group. This unique structure and its properties make it a versatile building block in the synthesis of pharmaceuticals and biologically active compounds. It has been explored for its potential applications in various fields, including antifungal and antibacterial properties, modulation of biological processes, and the development of new materials.
Uses
Used in Pharmaceutical Synthesis:
(R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure allows for the creation of novel molecules with potential therapeutic applications.
Used in Antifungal and Antibacterial Applications:
In the field of infectious diseases, (R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid is used as an active agent for the development of new antifungal and antibacterial drugs. Its potential to modulate biological processes makes it a promising candidate for combating resistant strains of bacteria and fungi.
Used in Biological Research:
(R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid is used as a research tool to study the modulation of certain biological processes. Understanding its interactions with biological systems can lead to the discovery of new therapeutic targets and strategies.
Used in Material Science:
In the field of material science, (R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid is used as a building block for the synthesis of complex organic compounds. Its unique properties may contribute to the development of new materials with specific characteristics and applications.
Used in Chemical Synthesis:
(R)-1-(1-phenylethyl)-1H-Pyrrole-2-carboxylic acid is used as a versatile starting material in chemical synthesis, particularly for the creation of complex organic molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 173989-76-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,9,8 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 173989-76:
(8*1)+(7*7)+(6*3)+(5*9)+(4*8)+(3*9)+(2*7)+(1*6)=199
199 % 10 = 9
So 173989-76-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO2/c1-10(11-6-3-2-4-7-11)14-9-5-8-12(14)13(15)16/h2-10H,1H3,(H,15,16)/t10-/m1/s1
173989-76-9Relevant articles and documents
Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors
Teng, Xin,Keys, Heather,Yuan, Junying,Degterev, Alexei,Cuny, Gregory D.
body text, p. 3219 - 3223 (2009/04/06)
Necroptosis is a regulated caspase-independent cell death pathway resulting in morphology reminiscent of passive non-regulated necrosis. Several diverse structure classes of necroptosis inhibitors have been reported to date, including a series of [1,2,3]thiadiazole benzylamide derivatives. However, initial evaluation of mouse liver microsome stability indicated that this series of compounds was rapidly degraded. A structure-activity relationship (SAR) study of the [1,2,3]thiadiazole benzylamide series revealed that increased mouse liver microsome stability and increased necroptosis inhibitory activity could be accomplished by replacement of the 4-cyclopropyl-[1,2,3]thiadiazole with a 5-cyano-1-methylpyrrole. In addition, the SAR and the cellular activity profiles, utilizing different cell types and necroptosis-inducing stimuli, of representative [1,2,3]thiadiazole and pyrrole derivatives were very similar suggesting that the two compound series inhibit necroptosis in the same manner.
New chiral rhodium(II) carboxylates and their use as catalysts in carbenoid transformations
Ferris, Leigh,Haigh, David,Moody, Christopher J.
, p. 107 - 110 (2007/10/02)
New chiral dirhodium(II) carboxylates 11-15 have been prepared from the half phthalate esters 6-8 and the pyrroles 9 and 10, and their use as catalysts for the decomposition of diazocarbonyl compounds 16 and 18 investigated.
