174485-36-0

Basic information

• Product Name: 3-(4-fluorophenyl)-N-methoxy-N-methylpropanamide
• Synonyms: 3-(4-fluorophenyl)-N-methoxy-N-methylpropanamide
• CAS NO: 174485-36-0
• Molecular Weight: 211.236
• Mol File: 174485-36-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-(4-fluorophenyl)-N-methoxy-N-methylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-fluorophenyl)-N-methoxy-N-methylpropanamide(174485-36-0)
• EPA Substance Registry System: 3-(4-fluorophenyl)-N-methoxy-N-methylpropanamide(174485-36-0)

Safety Data

• Hazardous Substances Data: 174485-36-0(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 136265-10-6 ethyl 4-fluorocinnamate 
• 772-70-3 3-(4-fluorophenyl)propanoyl chloride 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 459-31-4 3-(4-fluorophenyl)propanoic acid 

Downstream Products

• 1267878-41-0 1,1,1-trifluoro-4-(4-fluorophenyl)butan-2-one 
• 852661-49-5 1-((1R,2S,4R)-2-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-4-pivalamidocyclohexyl)-3-(5-ethyl-1,3,4-thiadiazol-2-yl)urea 
• 852660-75-4 N-(3-acetylphenyl)-N'-[(1R,2S,5R)-5-(N-methyl)acetamido-2-[N-propyl-3-(4-fluorophenyl)propylamino]methyl-cyclohexyl]urea 
• 852660-76-5 N-(3-acetylphenyl)-N'-[(1R,2S,5S)-5-(N-methyl)acetamido-2-[N-propyl-3-(4-fluorophenyl)propylamino]methyl-cyclohexyl]urea 
• 852661-48-4 1-((1R,2S,4R)-2-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-4-pivalamidocyclohexyl)-3-(5-methyl-1,3,4-thiadiazol-2-yl)urea 
• 852661-43-9 1-((1R,2S,4R)-2-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-4-pivalamidocyclohexyl)-3-(1,3,4-thiadiazol-2-yl)urea 
• 852660-79-8 C₂₇H₃₅FN₂O₃ 
• 852661-47-3 N-((1R,3S,4R)-4-amino-3-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-cyclohexyl)pivalamide 
• 852660-82-3 C₂₂H₃₆FN₃O 
• 852660-77-6 3-(4-fluorophenyl)-N-propylpropan-1-amine 
• 63416-70-6 3-(4-fluorophenyl)propanal 

Relevant articles and documents

'Wake-Up Call of A Sleeping Beauty': Straightforward Synthesis of Functionalized β-(2-Pyridyl) Ketones from 2,6-Lutidine

β-(2-Pyridyl) ketones are a unique class of heterocycles with valuable physicochemical properties and emerging relevance as pharmacophores. Herein we report a one-step process for the preparation of various substituted β-(2-pyridyl) ketones from the common starting material, 2,6-lutidine. Furthermore, we demonstrate the utility of this building block by synthesizing of a small set of antimalarial natural products.

A Weinreb amide approach to the synthesis of trifluoromethylketones

A novel route to access trifluoromethylketones (TFMKs) from Weinreb amides is reported. This represents the first documented case of the Ruppert-Prakash reagent (TMS-CF3) reacting in a constructive manner with an amide and enables synthesis of TMFKs without risk of over-trifluoromethylation.

NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY

A compound of the formula (I): wherein Z4, Z5 and Z9 each is independently carbon atom or nitrogen atom; Y is hydroxy, mercapto or amino; RA is a group of the formula: (wherein C ring is nitrogen-containing heteroaryl) has an inhibitory activity against integrase.