174621-52-4

Basic information

• Product Name: 1H-Indole, 1-(4-bromophenyl)-
• Synonyms: 1-(4-Bromophenyl)-1H-indole;N-p-bromophenylindole;1-(4-bromophenyl)indole;N-(4-bromophenyl)-1H-indole;N-p-bromophenyl indole;N-(4-bromophenyl)indole;1-(4-Bromo-phenyl)-1H-indole
• CAS NO: 174621-52-4
• Molecular Formula: C14H10BrN
• Molecular Weight: 272.144
• Mol File: 174621-52-4.mol
• Article Data: 24

Chemical Properties

• Melting Point: 64 - 65 °C
• Boiling Point: 370.8±34.0 °C(Predicted)
• Density: 1.38±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole, 1-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-(4-bromophenyl)-(174621-52-4)
• EPA Substance Registry System: 1H-Indole, 1-(4-bromophenyl)-(174621-52-4)

Safety Data

• Hazardous Substances Data: 174621-52-4(Hazardous Substances Data)

Usage

Description

1H-Indole, 1-(4-bromophenyl)-, also known as 4-Bromoindole, is an organic compound that belongs to the class of heterocyclic compounds known as indoles. It is composed of a bicyclic structure containing an indole ring fused to a benzene ring with a bromine atom substitution at the para position of the phenyl group. This chemical is commonly used as a building block and intermediate in the synthesis of various pharmaceuticals, agrochemicals, and materials. It is also utilized in the production of dyes and pigments. Additionally, 4-Bromoindole has shown potential biological activities, including antimicrobial, anti-inflammatory, and anticancer properties, making it an important target for medicinal research and drug development.

Uses

Used in Pharmaceutical Industry:
1H-Indole, 1-(4-bromophenyl)is used as a building block and intermediate for the synthesis of various pharmaceuticals due to its potential biological activities, including antimicrobial, anti-inflammatory, and anticancer properties.
Used in Agrochemical Industry:
1H-Indole, 1-(4-bromophenyl)is used as a building block and intermediate for the synthesis of various agrochemicals, contributing to the development of new and effective products in this field.
Used in Material Science:
1H-Indole, 1-(4-bromophenyl)is used as a building block and intermediate in the synthesis of various materials, enhancing their properties and expanding their applications.
Used in Dye and Pigment Production:
1H-Indole, 1-(4-bromophenyl)is used in the production of dyes and pigments, providing a wide range of colors and improving the performance of these products.
Used in Medicinal Research and Drug Development:
1H-Indole, 1-(4-bromophenyl)is used as an important target for medicinal research and drug development due to its potential biological activities and its role as a building block and intermediate in the synthesis of various pharmaceuticals.

Upstream product

• 120-72-9 indole 
• 5467-74-3 4-Bromophenylboronic acid 
• 106-37-6 1.4-dibromobenzene 
• 589-87-7 1,4-bromoiodobenzene 
• 65826-67-7 bis(4-bromophenyl)iodonium bromide 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 796095-77-7 4'-Indol-1-yl-biphenyl-4-carbaldehyde 
• 25699-92-7 4-(1H-indol-1-yl)benzonitrile 
• 1394958-96-3 1-(4-{3,12-dihydroxy-12-[4-(1H-indol-1-yl)phenyl]-6,9-dimethoxy-6,9-diphenyl-1,14-bis[tris(propan-2-yl)silyl]tetradeca-1,4,7,10,13-pentayn-3-yl}phenyl)-1H-indole 
• 1394959-03-5 1-(4-{12-[4-(1H-indol-1-yl)phenyl]-6,9-diphenyl-1,14-bis[tris(propan-2-yl)silyl]tetradeca-3,4,5,9,10,11-hexaen-1,7,13-triyn-3-yl}phenyl)-1H-indole 
• 1394958-90-7 1,10-bis[4-(1H-indol-1-yl)phenyl]-4,7,13,16-tetramethoxy-4,7,13,16-tetraphenylcyclooctadeca-2,5,8,11,14,17-hexayne-1,10-diol 
• 1394958-91-8 1-(4-{10-[4-(1H-indol-1-yl)phenyl]-4,7,13,16-tetraphenylcyclooctadeca-1,2,3,7,8,9,13,14,15-nonaen-5,11,17-triyn-1-yl}phenyl)-1H-indole (p-bis(4-(indol-1-yl)phenyl)-tetra-phenyl-carbobenzene) 
• 1264995-26-7 (-)-ethyl (R)-2-(1-(4-bromophenyl)-1H-indol-3-yl)hexanoate 

Relevant articles and documents

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COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND A ELECTRONIC DEVICE THEREOF

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SBA-15-functionalized melamine-pyridine group-supported palladium(0) as an efficient heterogeneous and recyclable nanocatalyst for N-arylation of indoles through Ullmann-type coupling reactions

SBA-15-functionalized melamine-pyridine group-supported palladium(0) was found to serve as a heterogeneous and recyclable nanocatalyst for N-arylation of indoles with aryl iodides under a low catalyst loading (0.3mol% of Pd) through Ullmann-type C￡N coupling reactions. A variety of aryl iodides could be aminated to provide the N-arylated products in good to excellent yields without the need of an inert atmosphere. Also, this catalyst was found to be an efficient system for the N-arylation of other nitrogen-containing heterocycles with aryl iodides. The heterogeneous palladium catalyst could be recovered by simple filtration of the reaction solution and reused for six cycles without significant loss in its activity.