174636-18-1

Basic information

• Product Name: (S)-N-(1-phenylpropyl)-3-bromo-2-phenylquinoline-4-carboxamide
• Synonyms: (S)-N-(1-phenylpropyl)-3-bromo-2-phenylquinoline-4-carboxamide
• CAS NO: 174636-18-1
• Molecular Weight: 445.359
• Mol File: 174636-18-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-N-(1-phenylpropyl)-3-bromo-2-phenylquinoline-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(1-phenylpropyl)-3-bromo-2-phenylquinoline-4-carboxamide(174636-18-1)
• EPA Substance Registry System: (S)-N-(1-phenylpropyl)-3-bromo-2-phenylquinoline-4-carboxamide(174636-18-1)

Safety Data

• Hazardous Substances Data: 174636-18-1(Hazardous Substances Data)

Upstream product

• 613-89-8 2-Aminoacetophenone 
• 91-56-5 indole-2,3-dione 
• 36735-26-9 3-amino-2-phenylquinoline-4-carboxylic acid 
• 57464-25-2 2-phenyl-3-bromoquinoline-4-carboxylic acid 
• 174636-20-5 2-phenyl-4-(carboxy-(S)-α-ethylbenzylamine)quinoline 
• 3789-59-1 (R)-1-phenylpropylamine 
• 57464-07-0 3-bromo-2-phenyl-quinoline-4-carbonyl chloride 

Downstream Products

• 174635-69-9 (-)-(S)-N-(α-ethylbenzyl)-3-methyl-2-phenylquinoline-4-carboxamide 
• 174636-20-5 2-phenyl-4-(carboxy-(S)-α-ethylbenzylamine)quinoline 

Relevant articles and documents

Functionalization through lithiation of (S)-N-(1-phenylpropyl)-2- phenylquinoline-4-carboxamide. Application to the labeling with carbon-11 of NK-3 receptor antagonist SB 222200

Lithiation of (S)-N-(1-phenylpropyl)-2-phenylquinoline-4-carboxamide with the complex n-BuLi/TMEDA (1/1 molar ratio) in THF at -60 °C for 5 h occurred selectively at the position 3 of the quinoline ring. This selectivity was shown by the absence of racemi