17474-27-0

Basic information

• Product Name: Malonic acid, (p-hydroxybenzylidene)-, cyclic isopropylidene ester
• Synonyms: Malonic acid, (p-hydroxybenzylidene)-, cyclic isopropylidene ester;2,2-Dimethyl-5-(4-hydroxybenzylidene)-1,3-dioxane-4,6-dione;5-(4-Hydroxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione;5-[(4-Hydroxyphenyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS NO: 17474-27-0
• Molecular Formula: C₁₃H₁₂O₅
• Molecular Weight: 248.23
• Mol File: 17474-27-0.mol
• Article Data: 38

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Malonic acid, (p-hydroxybenzylidene)-, cyclic isopropylidene ester(CAS DataBase Reference)
• NIST Chemistry Reference: Malonic acid, (p-hydroxybenzylidene)-, cyclic isopropylidene ester(17474-27-0)
• EPA Substance Registry System: Malonic acid, (p-hydroxybenzylidene)-, cyclic isopropylidene ester(17474-27-0)

Safety Data

• Hazardous Substances Data: 17474-27-0(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 2878-50-4 α-(4-hydroxyphenyl)-N-phenyl nitrone 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 1312791-61-9 C₂₀H₁₇NO₄ 
• 865234-02-2 methyl 3-(4-hydroxyphenyl-1-propynyl)propanoate 
• 1312791-71-1 methyl 3-[4-(benzyloxy)phenyl]hex-4-ynoate 
• 1073545-86-4 5-(cyclopropyl(4-hydroxyphenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Relevant articles and documents

Innovative bio-based organic UV-A and blue light filters from Meldrum's acid

Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based mole

Microwave-associate synthesis of Co3O4 nanoparticles as an effcient nanocatalyst for the synthesis of arylidene barbituric and Meldrum's acid derivatives in green media

In this study, Co3O4 nanocatalysts were constructed in environmentally appropriate conditions using controlled, effective, and facile microwave method. The final nanostructures were characterized by SEM, XRD, and TEM analyses. The products had a small size distribution, homogeneous morphology, and crystallographic structures associated with the formation of Co3O4 nanostructures. Moreover, EDS mapping analysis confirmed the existence of Co and O elements in the final structure, and the magnetic properties of the samples were investigated by VSM. The application of this nanostructure in a catalytic process was further examined, and the results suggested that it could be used as a novel candidate for the synthesis of arylidene barbituric and Meldrum,s acid through Knoevenagel condensation of aldehydes by barbituric and Meldrum,s acid in aqueous media. The high yield of these nanocatalysts would be justified by the nature of the nanostructure as well as the experimental procedure developed in this study, which affected the physicochemical features of the products.

An alternative, practical, and ecological protocol for synthesis of arylidene analogues of Meldrum’s acid as useful intermediates

This paper presents an ecological protocol for Knoevenagel condensation using a catalytic amount of 4,4′-trimethylenedipiperidine as a versatile, efficient, safe, commercially available, inexpensive, and recyclable organocatalyst by a ball-milling process